Luis Alberto Diaz, Jr., MD

About Me

I am the Head of the Division of Solid Tumor Oncology in Memorial Sloan Kettering’s Department of Medicine. I am also a medical oncologist who cares for people with advanced colon cancer and pancreatic cancer and a researcher applying cancer genetics to find new ways to diagnose and treat the disease. I will begin seeing patients at MSK in the near future.

My research focuses on applied cancer genetics. The more we learn about a tumor’s makeup, the more precise targets and diagnostics we can create against it — including immunotherapy treatments, which harness the body’s immune system to fight cancer. I am also very interested in how we can use cancer genetics to screen for, detect, diagnose, and monitor cancer by looking at DNA in tumor tissue and by using liquid biopsies.

With my colleagues, I am working to develop a “molecular pap smear” that is able to diagnose early-stage ovarian cancer and endometrial cancer based on these genetic markers — a crucial advance that would mean we could catch more instances of these cancers and begin treating them as quickly as possible. The test is currently in clinical trials. My hope is that we will start seeing this as part of the standard of care within the next few years.

As part of my role as Head of Solid Tumor Oncology, I am also working to improve mentorship for our young scientists and communication between researchers and departments across MSK. I am also involved in projects to improve our patients’ experience as well as their access to our unmatched cancer care.

I strive to support my patients at every step of the way throughout their treatment. The patients I see are often facing a lethal diagnosis. It’s important that they feel as though, along with the rest of their treatment team, we’re all in this together. 

  • Clinical Expertise: Colorectal Cancer; Pancreatic Cancer; Bile Duct Cancer; Neuroendocrine Tumors of the GI Tract
  • Awards and Honors: AACR Team Science Award (2013, 2014, 2017)
  • Languages Spoken: English; Spanish
  • Education: MD, University of Michigan
  • Residencies: The Johns Hopkins School of Medicine
  • Fellowships: The Johns Hopkins School of Medicine
  • Board Certifications: Medical Oncology


Visit PubMed for a full listing of Luis Alberto Diaz, Jr.’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Clinical Trials

As home to one of the world’s top cancer research centers, Memorial Sloan Kettering is typically involved in more than 900 clinical trials at a given time. Currently, clinical trials focused on the conditions I treat are enrolling new patients. If you’re interested in joining a clinical trial, click to learn about the trial’s purpose, eligibility criteria, and how to get more information.

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Most major health insurers offer plans that include MSK as one of their in-network providers. If MSK is in-network, it means all our doctors are too. Medicaid and New York State Medicare also provide benefits for care at MSK.

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