About Your Prostate Biopsy With Ultrasound Under Anesthesia

This information will help you get ready for your prostate biopsy with ultrasound and anesthesia (medication to make you sleep during a procedure) at Memorial Sloan Kettering (MSK). It will also help you understand what to expect after your procedure.

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About Your Prostate Biopsy

Your prostate is a small, firm gland about the size of a walnut. It’s in front of your rectum, below your bladder (see Figure 1). Your prostate works with other glands in your body to make semen. It surrounds your urethra (the tube that drains urine (pee) from your bladder).

Figure 1. Your prostate and surrounding organs

Figure 1. Your prostate and surrounding organs

A prostate biopsy is a procedure to collect small pieces of tissue from your prostate. An ultrasound is an imaging scan that uses sound waves to make pictures of the inside of your body. Your healthcare provider will use ultrasound imaging during your biopsy to help them take tissue from the right areas of your prostate.

After your biopsy, the pieces of tissue will be looked at under a microscope to check for abnormal cells.

‌  Your prostate biopsy with ultrasound is scheduled for
___________________ (date) with
___________________ (healthcare provider).

 
 
 
 

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Getting Ready for Your Procedure

Talk with your healthcare provider

Tell your healthcare provider if you:

  • Take anticoagulants (blood thinners). These are medications that affect the way your blood clots.
  • Take steroids, such as prednisone (Deltasone®).
  • Take any other medications, including vitamin E, multivitamins, herbal remedies, or any other dietary supplements or home remedies.
  • Have taken any antibiotics in the past 3 months.

Buy your supplies

Buy the following supplies before your procedure:

  • 1 saline enema (such as a Fleet® saline enema). You can buy this at your local pharmacy without a prescription.
  • Oral antibiotic (antibiotic that you swallow), if your healthcare provider tells you to. If you’re taking an oral antibiotic, your healthcare provider will give you a prescription. Read the “Antibiotics” section for more information.

Arrange for someone to take you home

You must have a responsible care partner take you home after your procedure. Make sure to plan this before the day of your procedure.

If you don’t have someone to take you home, call one of the agencies below. They’ll send someone to go home with you. There’s usually a charge for this service, and you’ll need to provide transportation. It’s okay to use a taxi or car service, but you must still have a responsible care partner with you.

Agencies in New York                                     Agencies in New Jersey
Partners in Care: 888-735-8913                                     Caring People: 877-227-4649
Caring People: 877-227-4649                                      

 

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7 Days Before Your Procedure

Stop taking certain medications

You may need to stop taking some of your medications before your procedure. Examples include anticoagulants, aspirin, medications that contain aspirin, multivitamins, and vitamin E. Talk with your healthcare provider about which medications are safe for you to stop taking. Follow their instructions. You can read about medications that contain aspirin and vitamin E in the resource Common Medications Containing Aspirin, Other Nonsteroidal Anti-inflammatory Drugs (NSAIDs), or Vitamin E.

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2 Days Before Your Procedure

Stop taking nonsteroidal anti-inflammatory drugs (NSAIDs)

Stop taking NSAIDs, such as ibuprofen (Advil®, Motrin®) and naproxen (Aleve®), 2 days before your procedure. These medications can cause bleeding. For more information, read the resource Common Medications Containing Aspirin, Other Nonsteroidal Anti-inflammatory Drugs (NSAIDs), or Vitamin E.

 
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The Day Before Your Procedure

A staff member from the Admitting Office will call you after 2:00 pm the day before your procedure. If your procedure is scheduled for a Monday, they will call you the Friday before. If you don’t get a call by 7:00 pm, call 212-639-5014.

The staff member will tell you what time to arrive at the hospital for your procedure. They’ll also remind you where to go on the day of your procedure. This will be one of the following locations:

  • Presurgical Center (PSC) on the 2nd floor
    1275 York Avenue
    (between East 67th and East 68th Streets)
    M Elevator to 2nd Floor
  • Presurgical Center (PSC) on the 6th floor
    1275 York Avenue
    (between East 67th and East 68th Streets)
    B elevator to 6th Floor
  • Josie Robertson procedure Center (JRSC)
    1133 York Avenue
    (between East 61st and East 62nd Streets)

If you have any changes in your health or you need to cancel your procedure for any reason, call your surgeon. Offices are usually open Monday through Friday from 9:00 am to 5:00 pm. After 5:00 pm, during the weekend, and on holidays, call 212-639-2000 and ask for the doctor that is covering for your doctor.

Instructions for eating and drinking before your procedure
12 ounces of water
  • Do not eat anything after midnight the night before your procedure. This includes hard candy and gum.
  • Between midnight and up until 2 hours before your scheduled arrival time, you may drink a total of 12 ounces of water (see figure).
  • Starting 2 hours before your scheduled arrival time, do not eat or drink anything. This includes water.
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The Day of Your Procedure

Give yourself a saline enema

Give yourself a saline enema (such as a Fleet® saline enema) the morning of your procedure. Follow the directions on the box.

Take your antibiotics

You will need to take an antibiotic to prevent infection from the biopsy. Your healthcare provider will tell you which antibiotic you will take and give you a prescription. You will take one of the antibiotics listed below.

Oral antibiotics

  • Ciprofloxacin (Cipro®) 500 mg (2 tablets)
  • Take 1 tablet 2 hours before your procedure.
  • Take 1 tablet 12 hours later.
  • Cefixime (Suprax®) 400 mg (1 tablet)
  • Take 1 tablet 2 hours before your procedure.
  • Cefuroxime (Ceftin®) 500 mg (2 tablets)
  • Take 1 tablet 2 hours before your procedure.
  • Take 1 tablet 12 hours later.
  • Sulfamethoxazole-trimethoprim (Bactrim®) 500mg (2 tablets)
  • Take 1 tablet 2 hours before your procedure.
  • Take 1 tablet 12 hours later.

Intravenous (IV) antibiotics

Your healthcare provider might decide you need IV antibiotics instead of oral antibiotics. If they do, you will get the IV medication through a vein in your arm while you’re in the hospital.

Things to remember

  • Don’t wear any metal objects. Remove all jewelry, including body piercings. The equipment used during your procedure can cause burns if it touches metal.
  • Don’t put on any lotion, cream, deodorant, makeup, powder, perfume, or cologne.
  • Leave valuables, such as credit cards, jewelry, and your checkbook, at home.
  • If you wear contact lenses, wear your glasses instead. Wearing contact lenses during procedure can damage your eyes. Remember to bring a case for them.
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During Your Procedure

  • When it’s time to change for procedure, you’ll get a hospital gown, robe, and nonskid socks to wear.
  • The exact starting time of procedure may depend on the length of the procedure scheduled before yours. Your nurse will speak with you if there are any unexpected delays.
  • Before you’re taken into the operating room, you’ll need to remove your hearing aids, dentures, prosthetic device(s), wig, and religious articles.

Visitors

Get ready for your procedure

  • When it’s time to change for procedure, you’ll get a hospital gown, robe, and nonskid socks to wear.
  • The exact starting time of procedure may depend on the length of the procedure scheduled before yours. Your nurse will speak with you if there are any unexpected delays.
  • Before you’re taken into the operating room, you’ll need to remove your hearing aids, dentures, prosthetic device(s), wig, and religious articles.

Your procedure will take about 20 to 30 minutes.

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After Your Procedure

After your procedure, you will need to urinate before you leave the hospital.

It’s normal to have some soreness or discomfort after your procedure, but most people don’t have pain. If you feel sore, you can take acetaminophen (Tylenol®). If the acetaminophen doesn’t help, call your doctor’s office.

For 3 days after your procedure, try to drink double the amount of liquids that you usually drink. This will help flush out your bladder, prevent infection, and minimize the amount of blood in your urine. It will also help soften your bowel movements (poop), which helps keep your rectum from getting irritated.

Temporary effects on your bowel movements, urine, and semen

  • You might see blood in your bowel movements. You might also have a small amount of bleeding from your rectum. These can happen right after your procedure or for the next few days when you have a bowel movement.
  • You might see blood in your urine for 7 to 14 days after your procedure. This bleeding might come and go.
  • Your semen might look rust-colored for up to 12 weeks after your procedure. This is because small amounts of blood might be in it.

Activity

  • Plan to stay within 2 hours of MSK for the first 24 hours after your procedure. If you have any problems after your procedure, such as fever or bleeding, you might have to go to MSK’s Urgent Care Center (UCC).
  • Don’t have sex for 3 days after your procedure.
  • For the next 5 days after your procedure, don’t play any sports, work out in a gym, ride a bicycle, or lift any objects heavier than 10 pounds (4.5 kilograms).

Test results

Your test results will be ready in 5 to 7 days after your biopsy. Your healthcare provider will contact you and explain the results to you. You can also ask for a copy of your results.

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When to Call Your Healthcare Provider

Call your healthcare provider right away if you have any of the following:

  • Have a fever of 101 °F (38.3 °C) or higher
  • Have heavy bleeding out of your rectum
  • Have bleeding out of your rectum that won’t stop
  • Can’t urinate
  • See bright red blood or large clots in your urine
  • Have shaking chills
  • Feel dizzy
  • Have any other problems, questions, or concerns
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Your feedback will help us improve the information we provide to patients and caregivers. We read every comment, but we’re not able to respond. If you have questions about your care, contact your healthcare provider.
 

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