Discharge Instructions After Your 3F8 or Hu3F8 Treatment

This information explains how to care for your child after their 3F8 or Hu3F8 immunotherapy treatment. For the rest of this resource, our use of the word “you” and “your” refers to you or your child.

You recently had 3F8 immunotherapy treatment to help treat your neuroblastoma or osteosarcoma. While most side effects associated with this treatment do not usually last longer than the week of treatment, there is a chance that you will experience some side effects after discharge.

Contact Information

For any issues during business hours, call your primary doctor at Memorial Sloan Kettering (MSK) Monday through Friday from 8:00 am to 6:00 pm.

Doctor: ____________________ Telephone: ____________________

After business hours, during the weekend, and on holidays, call 212-639-2000 and ask to speak with the pediatric fellow on call.

Urgent Care Center

You may need to go to MSK’s Pediatric Urgent Care Center (UCC) depending on the issue you are experiencing. The UCC is located on the 9th floor of Memorial Hospital. Take the M elevators to the 9th floor and check in at the M9 front desk. The closest entrance is located at 1275 York Avenue. This entrance is open 24 hours a day, 7 days a week.

 

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Common Side Effects

Pain

The most common side effect of 3F8 or Hu3F8 therapy is pain. While the pain is usually most severe during treatment, there can be pain after discharge. How much pain is felt varies from person to person.

Things to remember:
  • To prepare for any pain you may experience after discharge, make sure you have the pain medication your healthcare provider prescribes to you before you leave the hospital.
  • Do not take acetaminophen (Tylenol®) or ibuprofen (Advil® or Motrin®) to relieve pain unless instructed by your healthcare provider.
  • Take pain medication only as prescribed. If the medication is not controlling your pain or if you are having side effects (constipation, nausea, excessive drowsiness, or itching) from the medication, call your doctor.

Next dose of pain medication can be given at: _________ am / pm

Medication Name:_________________________

Medication Amount: _______ every _______ hours as needed for pain.

Allergic reactions

You may have an allergic reaction to 3F8 immunotherapy treatment in the form of hives, redness, and swelling. These reactions can happen at any time between treatments. Your healthcare provider may prescribe you medication to help with this.

Things to remember:

  • To prepare for any allergic reaction you may have after discharge, make sure you have the antihistamine medication your healthcare provider prescribed to you, such as hydroxyzine (Vistaril®) or diphenhydramine (Benadryl®), before you leave the hospital.

Next dose of antihistamine can be given at: _________ am / pm

Medication Name:_________________________

Medication Amount: ______ every ______ hours as needed for allergy symptoms.

Fever

You may have a fever (temperature of 100.4° F (38 ° C) or higher) after your treatment. The fever may be related to treatment or a sign of infection so it is important to call your doctor for further instructions.

A central line, or central venous catheter, is like an artificial vein. It will make it easier for your healthcare team to access your blood vessels for medications and tests. Central lines can collect bacteria and cause infection. If you have a central line and have a temperature of 100.4° F (38 ° C) or higher, or you have redness, swelling, or tenderness at the catheter site, call your doctor as soon as possible.

Does your child have a central line (MediPort®, Broviac®, PICC)?  YES / NO

Please see comment area below for further instructions:



Trouble going to the bathroom

You may be constipated or have trouble urinating. This is a common side effect of many pain medications. Your doctor may prescribe you medication to help you with urinating and moving your bowels.

 

What you can do:

  • Try using the bathroom with the sink running. This can help with urinating.
  • Apply a warm, wet cloth to your stomach below your belly button to promote urination.
  • Drink plenty of liquids.
  • Follow your doctor’s instructions for managing constipation.

Nausea and vomiting

You may experience some nausea and vomiting when you go home from the hospital. Your doctor may prescribe antinausea medication to help with this.

Next dose of antinausea medication can be given at: _________ am / pm

Medication Name:_________________________

Medication Amount: _______ every _______ hours as needed for nausea.

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Return to Clinic

Please return to clinic on______________ at______________am / pm
for _______________________________________________.

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Call Your Doctor or Nurse If:

  • You have not urinated in ______ hours or longer
  • You have not had a bowel movement in ________ days
  • You have pain that doesn’t get better or gets worse after taking your medication
  • You have uncontrolled nausea or vomiting
  • You vomit every time you drink something. This may cause dehydration.
  • You have a sudden headache that does not go away
  • You see changes in your mood or behavior that you find concerning
  • You have constant coughing
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Go to the UCC or Call 911 If You Have:

  • A temperature of 100.4° F (38 ° C) or higher
  • Shortness of breath
  • Difficulty breathing
  • Redness, swelling, or tenderness at the catheter site
  • Swelling of the lips, tongue, or throat
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