Chemotherapy for Soft Tissue Sarcoma

Our medical oncologists use the most sophisticated approaches to treating soft tissue sarcoma, including clinical trials of new therapies and drug combinations based on the specifics of your diagnosis whether you’ve had surgery, and other factors.

For some people, chemotherapy can cure or control your cancer or help ease symptoms. Our medical oncologists are familiar with the different chemotherapy regimens available, and can customize the best approach for you.

For some types of soft tissue sarcoma, we recommend that you receive chemotherapy to shrink the tumor before having surgery. This is called neoadjuvant therapy, and it allows our surgeons to perform a less extensive operation. We often use this approach to treat people with rhabdomyosarcoma and Ewing sarcoma. Other times, we may recommend chemotherapy after surgery to kill any cancer cells that might remain in the body, called adjuvant therapy.

You may receive chemotherapy through a pill or infusion in a vein. Many types of soft tissue sarcoma respond to standard chemotherapy agents.

Recurrent or Metastatic Disease

In some people, soft tissue sarcoma recurs (returns) after the first treatment. It can also spread to distant areas of the body in a process known as metastasis. If you have sarcoma that has returned or spread, our doctors may recommend that you receive chemotherapy while continuing to evaluate whether surgery will help you.

If the cancer doesn’t get better with chemotherapy, we may recommend you consider enrolling in a  clinical trial testing new investigative treatments.