Clinical Updates & Insights

Our clinical updates provide you with timely information about Memorial Sloan Kettering’s new treatment approaches, key clinical trials, and innovations in detecting and treating many cancers.

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233 Clinical Updates found
Intensity-modulated radiation therapy (IMRT)
Clinical Update
Less Risk of Femoral Fracture with Intensity-Modulated Radiation Therapy for Thigh and Groin Sarcoma

Intensity-modulated radiation therapy (IMRT) confers a lower risk of femoral fracture in patients with primary soft tissue sarcoma of the thigh or groin, despite a higher dose of radiation to the target volume compared to conventional radiation.
Doctors looking at x-ray
Clinical Update
Surgery Is Critical in Advanced Testicular Cancer

Resection of all residual disease after salvage chemotherapy offers the best chance for a cure for patients with refractory or relapsed advanced testicular cancer, according to the results of our recent retrospective study.
Robert Young
Clinical Update
Deep Learning with MRI-Radiomics Improves Survival Prediction in Glioblastoma

Incorporating radiomics with methyl guanine methyl transferase (MGMT) status can more accurately stratify glioblastoma patients into groups with different survival risks compared to using either prediction tool in isolation.
Video
Video: Expanding Organ Preservation Surgery in Esophageal Cancer

Daniela Molena, MD, Director, Esophageal Surgery Program, talks on expanding organ preservation surgery in esophageal cancer and the quest to pinpoint the elusive sentinel node in these patients.
The Most Recent Staging System for Thyroid Cancer Downgrades Almost One-Third of Cases
Clinical Update
The Most Recent Staging System for Thyroid Cancer Downgrades Almost One-Third of Cases

The newest edition of the thyroid cancer staging system has increased the age at diagnosis as a prognostic factor by a decade.
cancer smart
Clinical Update
Watch-and-Wait Strategy Results in Rectal Preservation for Select Rectal Cancer Patients

A carefully monitored, multidisciplinary watch-and-wait strategy can result in excellent rectal preservation and pelvic tumor control for a large majority of select patients with rectal cancer who show a clinical complete response after neoadjuvant therapy.
Robert Young, MD
Clinical Update
Case Study: Pituitary Carcinoma Response to Immunotherapy

Treating pituitary tumors with combination immunotherapy may be an effective treatment strategy, especially for tumors that are resistant to temozolomide.
Blood Vials
Clinical Update
Circulating Tumor DNA Analysis Allows Rapid Therapy Matching in Lung Cancer

Our recent prospective study data provides support for the incorporation of plasma next-generation sequencing (NGS) assays into lung cancer practice guidelines.
Pictured: Dr. Mario Leitao, Jr. and Dr. Nadeem Abu-Rustum
Sentinel Lymph Node Algorithm Noninferior to Full Pelvic Lymphadenectomy in Advanced Endometrial Cancer

Oncologic outcomes are similar with the use of a sentinel lymph node algorithm compared to performing a full pelvic and paraaortic lymph node dissection in node-negative patients with deeply invasive endometroid endometrial carcinoma.
Nadeem Abu-Rustum, MD, FACOG, FACS
Uterine-Preserving Surgery Achieves Same Oncologic Outcomes as Hysterectomy in Early-Stage Cervical Cancer

Uterine-preserving surgery results in excellent and similar five-year disease-specific survival compared to hysterectomy in young women with stage IB1 cervical cancer.