Clinical Updates & Insights

Our clinical updates provide you with timely information about Memorial Sloan Kettering’s new treatment approaches, key clinical trials, and innovations in detecting and treating many cancers.

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233 Clinical Updates found
Daniel Prince, MD, MPH
Distraction Osteogenesis: Optimal Bone Reconstruction in Pediatric Sarcoma

Although distraction osteogenesis is commonly employed in regular orthopedic surgery, its use in cancer patients is currently limited. But research shows that these durable reconstructions can provide superior opportunities for better long-term limb function and growth in this cohort.
Jodi V. Mones, MD
Managing Chemotherapy-Induced Thrombocytopenia: Romiplostim Research

Our recent research demonstrates that the thrombopoietin receptor agonist romiplostim effectively modifies chemotherapy-induced thrombocytopenia (CIT) in solid tumor patients, allowing a majority to resume chemotherapy
Dr. Paul Chapman
Video: Good News out of ASCO 2018 on Melanoma Treatment Data

Research presented at the 2018 meeting of the American Society of Clinical Oncology showed that the relapse rate is low for melanoma patients treated with immunotherapy, but those who do relapse can respond a second time to immunotherapy. Dr. Chapman discusses the impact. (June 2018)
Vial lying on a table
Prognostic Genetic Testing Underutilized in Chronic Lymphocytic Leukemia

Prognostic genetic testing is recommended for all patients with chronic lymphocytic leukemia (CLL). However, recent research shows that testing is infrequently performed and outcomes poorer in patients with unfavorable disease risk.
Kishwer S. Nehal
Advancing Care for Complex Skin Cancers

Unlike the clinical management of other types of cancer, a multidisciplinary approach is not the established norm for treating skin cancer, resulting in significantly limited opportunities to individualize patient care.
Mark Bilsky and Ilya Laufer
Mitigating Morbidities with Modern Approaches to Spinal Metastases

Spinal cord compression due to spinal metastases is a medical emergency. Modern treatment approaches have fundamentally shifted the paradigm from providing short-term palliation and pain relief to delivering durable tumor control with fewer morbidities than older approaches. Therefore, cancer patients who have symptoms of spinal cord compression should be referred for surgical evaluation as soon as possible.
Prasad Adusumilli
CAR T Cells Show Promise in Treating Mesothelioma and Pleural Malignancies

The preliminary results of our ongoing trial investigating CAR T cell therapy to treat patients with malignant pleural disease, including mesothelioma, show “encouraging clinical outcomes”
Mario E. Lacouture, MD
Preventing and Managing Alopecia in Breast Cancer Patients

Topical minoxidil can be of significant benefit to women with breast cancer who develop alopecia during treatment with endocrine therapies, our most recent research shows.
Video: Lymphoma Update: CAR T Therapies and Checkpoint Inhibitors

Lymphoma experts Anas Younes, MD and Andrew Zelenetz, MD, PhD discuss the fast evolving research on CAR T cells and checkpoint inhibitors that is yielding the novel treatment options improving both outcomes and quality of life for people with lymphoma.
kidney illustration
Kidney Cancer Surgery: Integrating Oncological and Renal Functional Concerns

Across the United States, there is a disparity in the rate of people who are candidates for a partial nephrectomy — those with small renal tumors — and those who actually have the procedure.