This information describes the common uses of Agaricus, how it works, and its possible side effects.

Common Name

Himematsutake, Agarikusutake, Kawarihiratake, Cogumelo do Sol, Sun mushroom

How It Works

Agaricus extract may benefit patients with certain cancers, but more studies are needed to confirm these observations.

Agaricus blazei is an edible mushroom grown in Brazil and Japan. It is used to treat arteriosclerosis, hepatitis, hyperlipidemia, diabetes, dermatitis, and cancer. Laboratory studies and experiments done in mice have shown that agaricus can stimulate the immune system and has anticancer effects. Compounds present in agaricus may prevent the formation of blood vessels needed for tumor development.

Purported Uses

  • Arteriosclerosis
    There are no clinical data to support this use.
  • Cancer treatment
    One study showed that oral agaricus extract improved quality of life in patients with gynecological cancers.
  • Chronic hepatitis
    Agaricus is used in traditional medicine to treat hepatitis. A small clinical study showed that agaricus helps improve liver function in patients with hepatitis B.
  • Diabetes
    There are limited laboratory data suggesting that agaricus mushroom has antidiabetic effects. One small clinical study showed that agaricus reduced blood glucose levels in healthy subjects.
  • Hyperlipidemia
    One small clinical study showed that agaricus reduced cholesterol level in healthy subjects.
  • Stimulant
    There are no clinical data to support this use.

Do Not Take If

  • You are allergic to agaricus or other mushrooms.
  • You are taking drugs that are substrates of Cytochrome P450 3A4: Agaricus may increase the risk of side effects of these drugs.

Side Effects

  • May cause liver damage in cancer patients.
  • Reports of lip swelling.