Recent MSK Discoveries & Advances

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Memorial Sloan Kettering researchers are relentlessly exploring every aspect of cancer — from basic investigations of cells and molecules to clinical trials of new treatments and population-wide studies of the disease. While our core mission is to translate this knowledge into new strategies to control cancer, many of our investigators are also making scientific progress against other diseases and conditions.

Below are some examples of discoveries and advances that recently were made in our laboratories and clinics, and featured in our blog, On Cancer.

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409 News Items found

Finding

How an Altered Gatekeeping Protein Can Cause Cancer

An MSK study explains how the drug selinexor, which was recently approved to treat multiple myeloma and is being tested in many other tumor types, stops cancer.

A micrograph of a cell nucleus

Finding

Scientists See Potential in Cellular “Death by Iron” for Cancer Treatment

This form of cell death is called ferroptosis, and certain cancer cells are especially vulnerable to it.

a man holding a shield and sword

In The Lab

Researchers Identify a Bacterial Species That Could Protect against Hospital-Acquired Infections

MSK researchers are reporting that a bacterial species called Blautia producta appears to release a substance that kills harmful bacteria.

Microscopy image of vancomycin-resistant Enterococcus

In the Lab

How Stem Cells Decide Their Fate

Research in blood stem cells has revealed new information about how these cells decide what to become when they divide.

An illustration of two teapots with liquid flowing into various cups

In the Lab

“Molecular Origami” Enables Proteins to Serve as Specialized Delivery Vehicles, Study Finds

Scientists at the Sloan Kettering Institute have identified a fundamentally new type of protein-sorting system in cells.

An illustration of proteins serving as bar-code-reading drones

In the Lab

Analyzing Urine Can Guide the Treatment of Childhood Kidney Tumors

A protein detected in the urine of children with Wilms’ tumor led to the development of a test to improve diagnosis and treatment.

Illustration of child with kidneys highlighted, cup of urine, and a beam of light.

Finding

Sugar Directly Controls a Cancer-Causing Protein, Scientists Find

The discovery suggests a potential new treatment approach for certain cancers.

An illustration of sugar pouring onto NRF2

In The Clinic

FDA Approves Pexidartinib, a Targeted Therapy for a Tumor of the Joints

Pexidartinib is the first drug approved specifically to treat tenosynovial giant cell tumor.

Medical oncologist William Tap

In The Clinic

Study Asks: Are Women Missing Out on BRCA Testing?

Results from a study of women with breast and ovarian cancer show surprisingly low rates of genetic testing.

doctor and patient