Recent Discoveries & Advances

Recent Discoveries & Advances

Memorial Sloan Kettering researchers are relentlessly exploring every aspect of cancer — from basic investigations of cells and molecules to clinical trials of new treatments and population-wide studies of the disease. While our core mission is to translate this knowledge into new strategies to control cancer, many of our investigators are also making scientific progress against other diseases and conditions.

Below are some examples of discoveries and advances that recently were made in our laboratories and clinics, and featured in our blog, On Cancer.

Search by keywords:

154 News Items found

In the Lab

Therapies that Target mTOR May Enable Some Cancer Cells to Grow

Research into the mTOR pathway is beginning to to explain why some targeted therapies don’t work as well as expected against certain types of cancer.

Cancer biologist Wilhelm Palm

Finding

Scientists Link Gene to Inherited Form of Childhood Leukemia

Researchers have found that some cases of acute lymphoblastic leukemia in children may be linked to an inherited gene mutation.

Child hand with IV holding adult hand.

In the Clinic

Experimental Drug Targets Rare Joint Disorder

A new targeted therapy is showing promise in treating tenosynovial giant-cell tumor, a joint disease also known as pigmented villonodular synovitis.

MRI image of a tumor behind the knee.

In the Lab

Discovery Could Boost New Therapies for Myeloproliferative Neoplasms

Researchers have discovered a way to potentially make drugs more effective at treating certain blood cancers.

Illustration of normal blood cells (red discs) along with cancer cells (black spheres) floating through a blood vessel.

Q&A

A Field in Motion: Fighting Cancer with Exercise

Exercise as a cancer treatment? Too good to be true? Perhaps not. Exercise scientist Lee Jones is teasing out the answer to this and other questions. Here, he talks to us about his work.

Q&A

Picturing the Body’s Immune Response

Cell biologist Philipp Niethammer discusses what the zebrafish can teach us about how the body heals.

In the Lab

Manipulating a Single Gene Turns Colorectal Cancer Cells Back to Normal

For the first time, scientists have shown that the gene APC, which is mutated in the vast majority of colorectal cancers, might be a promising target for future therapies.

Organoid cell structures fluorescing in blue, green, and purple.

In the Lab

Uncharted Waters: The Making of a New Cancer Drug

A team of scientists is combining sophisticated chemistry and experiments in zebrafish to develop a new cancer drug that shows early potential against melanoma and metastatic breast cancer.

Portrait of a live zebrafish with dark patterning around and above the eyes

In the Lab

Miniature Device Could Unlock the Promise of Some Kidney Cancer Drugs

Memorial Sloan Kettering scientists have engineered a tiny particle that could ferry drugs directly to the kidneys and prevent their uptake in other organs.

Proximal tubule of the kidney.

In the Lab

From Blob to Fly: How Cells Work Together to Shape the Body and Its Organs

Learn about the spectacular research taking place in the laboratory of developmental biologist Jennifer Zallen, who was recently elected a Howard Hughes Medical Institute Investigator.