Recent Discoveries & Advances

Recent Discoveries & Advances

Memorial Sloan Kettering researchers are relentlessly exploring every aspect of cancer — from basic investigations of cells and molecules to clinical trials of new treatments and population-wide studies of the disease. While our core mission is to translate this knowledge into new strategies to control cancer, many of our investigators are also making scientific progress against other diseases and conditions.

Below are some examples of discoveries and advances that recently were made in our laboratories and clinics, and featured in our blog, On Cancer.

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148 News Items found

In the Lab

Manipulating a Single Gene Turns Colorectal Cancer Cells Back to Normal

For the first time, scientists have shown that the gene APC, which is mutated in the vast majority of colorectal cancers, might be a promising target for future therapies.

Organoid cell structures fluorescing in blue, green, and purple.

In the Lab

Uncharted Waters: The Making of a New Cancer Drug

A team of scientists is combining sophisticated chemistry and experiments in zebrafish to develop a new cancer drug that shows early potential against melanoma and metastatic breast cancer.

Portrait of a live zebrafish with dark patterning around and above the eyes

In the Lab

Miniature Device Could Unlock the Promise of Some Kidney Cancer Drugs

Memorial Sloan Kettering scientists have engineered a tiny particle that could ferry drugs directly to the kidneys and prevent their uptake in other organs.

Proximal tubule of the kidney.

In the Lab

From Blob to Fly: How Cells Work Together to Shape the Body and Its Organs

Learn about the spectacular research taking place in the laboratory of developmental biologist Jennifer Zallen, who was recently elected a Howard Hughes Medical Institute Investigator.

In the Clinic

Landmark Melanoma Study Bears Out the Success of Combination Immunotherapy

A major international trial shows that the drugs ipilimumab and nivolumab can produce powerful responses against advanced melanoma if given together.

MSK medical oncologist and immunologist Jedd Wolchok

Finding

Looking Under the Hood of Aggressive Leukemia

A new study shows how different gene mutations make leukemia more aggressive and yields clues about possible treatments.

Ross Levine

Finding

Flanking Maneuver: Drug Combination Might Outsmart Resistant Head and Neck Cancers

Lab findings have suggested that a new combination of targeted therapies could be successful against certain head and neck cancers.

Investigator Maurizio Scaltriti

In the Clinic

Combination Immunotherapy Produces Striking Results against Melanoma

Giving two immunotherapy drugs together produced dramatic results in patients with advanced melanoma.

A smiling physician in white coat talking to patient whose back is to the camera.

Announcement

A Sampling of Promising Cancer Science Highlighted at Major Meeting

MSK physician-scientists reported hopeful news from several clinical studies at the annual meeting of the American Association for Cancer Research.

MSK Physician-in-Chief José Baselga

In the Lab

Why a New Immunotherapy for Lung Cancer Works for Only Some People

According to an MSK study, a powerful immunotherapy drug for lung cancer works better in people whose tumors carry a lot of mutations caused by tobacco smoke.

Cancer genomics researcher Timothy Chan