Stefan Kachala

Research Fellow

Stefan Kachala

Research Fellow

Awards and Scholarships

  • American College of Surgeons Research Scholarship
  • C. Walton Lillehei Resident Forum (AATS) Finalist

Current Employment

  • Cardiothoracic Surgery Fellow, Cleveland Clinic, Cleveland, OH

Publications

Manuscripts 

  • Kachala SS, Bograd AJ, Villena-Vargas J, Suzuki K, Servais EL, Kadota K,  Chou J, Sima CS, Vertes E, Rusch VW, Travis WD, Sadelain M, Adusumilli PS. Mesothelin Overexpression Is a Marker of Tumor Aggressiveness and Is Associated with Reduced Recurrence-free and Overall Survival in Early-Stage Lung Adenocarcinoma. Clin Cancer Res. 2014 Feb 15;20(4):1020-8. PMID: 24334761; PMCID: PMC3944669.
  • Kadota K, Kachala SS, Nitadori J, Suzuki K, Dunphy MPS, Sima CS, Travis WD, Rusch VW, Adusumilli PS. High-SUVmax on FDG-PET indicates pleomorphic subtype in epithelioid malignant pleural mesothelioma: supportive evidence to reclassify pleomorphic as non-epithelioid histology. J Thorac Oncol. 2012 Jul;7(7):1192-7. PMID: 22617244; PMCID: PMC3691682.
  • Servais EL, Colovos C, Kachala S, Adusumilli PS. Pre-clinical mouse models of primary and metastatic pleural cancers of the lung and breast and the use of bioluminescent imaging to monitor pleural tumor burden. Curr Protoc Pharmacol 2011 Sep;Chapter 14:Unit14.21. PMID 21898334.
  • Suzuki K, Kachala SS, Kadota K, Shen R, Mo Q, Beer DG, Rusch VW, Travis WD, Adusumilli PS. Prognostic immune markers in non-small cell lung cancer. Clin Cancer Res 2011 Aug 15;17(16):5247-56. PMID 21659461.
  • Suzuki K, Servais EL, Rizk NP, Solomon SB, Sima CS, Park BJ, Kachala SS, Zlobinsky M, Rusch VW, Adusumilli PS. Palliation and pleurodesis in malignant pleural effusion: the role for tunneled pleural catheters. J Thorac Oncol. 2011 Apr;6(4):762-7. PMID 21325982.
  • Kachala SS, Servais ES, Park BJ, Rusch VW, Adusumilli PS. Therapeutic sentinel lymph node imaging. Semin Thor Cardiovasc Surg 2009 Winter;21(4):327-38. PMID 20226346.

Abstracts/Presentations 

  • Bograd A, Villena-Vargas J, Kachala S, Servais E, Colovos C, Rodriguez L, Rusch VW, Sadelain M, Adusumilli PS. Mesothelin-targeted T-cell therapy optimized for the lung adenocarcinoma tumor microenvironment. International Association for the Study of Lung Cancer (IASLC) 15th World Conference on Lung Cancer, October 27-30, 2013, Sydney, Australia.
  • Kachala S, Bograd AJ, Rodriguez L, Servais EL, Kadota K, Sima C, Rusch VW, Travis WD, Sadelain M, Adusumilli PS. Mesothelin decreases recurrence-free survival in lung adenocarcinoma by imparting an aggressive phenotype. American Association for Thoracic Surgery meeting. May 4-8, 2013; Minneapolis. MN (Oral Presentation).
  • Kachala SS, Suzuki K, Vertes E, Rodriguez L, Kadota K, Sima CS, Rusch VW, Travis WD, Sadelain M, Adusumilli PS. Mesothelin is a commonly expressed tumor marker in lung adenocarcinoma (LAC) that imparts an aggressive phenotype—a candidate molecular target. International Association for the Study of Lung Cancer (IASLC) 14th World Conference on Lung Cancer, July 2-5, 2011, Amsterdam, The Netherlands.
  • Servais EL, Colovos C, Kachala SS, Rodriguez L, Kadota K, Rusch VW, Sadelain M, Adusumilli PS. Mesothelin expression promotes invasive phenotype and matrix metalloproteinase secretion in pleural mesothelioma. 10th International Conference of the International Mesothelioma Interest Group (IMIG), August 31-September 3, 2010, Kyoto, Japan.
  • Suzuki K, Servais EL, Sima C, Kachala SS, Rizk NP, Park B, Rusch VW, Adusumilli PS. Outcomes of indwelling tunneled pleural catheters for malignant pleural effusion: the role for surgical evaluation. Oral presentation in surgical forum: American College of Surgeons 96th Annual Clinical Congress, October 3-7, 2010, Washington, DC.
  • Colovos C, Servais EL, Kachala SK, Rodriguez L, Kadota K, Rusch VW, Sadelain M, Adusumilli PS. Significance of tumor microenvironment in preclinical investigation of malignant pleural mesothelioma. International Symposium on Malignant Mesothelioma, June 10-12, 2010, Washington, DC.