Hospital Research Teams
The Precision Cellular Therapy Laboratory
Overview
Roni Shouval
Director
The Precision Cellular Therapy Laboratory is dedicated to advancing the understanding and effectiveness and safety of cellular therapies. Our research primarily focuses on uncovering drivers and mechanisms of resistance and toxicity that challenge the success of cellular therapies such as chimeric antigen receptor T-cell therapy and hematopoietic cell transplantation. By integrating multiomic approaches and novel computational techniques, we strive to identify and decode the biological drivers of disease resistance and adverse outcomes. Our goal is to translate these insights into more precise and safer therapeutic strategies, ultimately enhancing patient outcomes in hematologic malignancies and beyond.
Current Projects:
- Synthesizing multimodal data for prediction of CAR-T cell therapy outcome
- Uncovering genomic drivers of resistance to CAR-T cell therapy in lymphoma
- Dynamic Modeling of Cellular Therapy Toxicity
People
Director
Members
Computational Biologist
Assistant Attending
Adult Cancer Immunotherapy Fellow
Visiting Investigator
Research Fellow
Visiting Investigator
Visiting Investigator
Assistant Attending Biostatistician
Research Fellow
Clinical and Laboratory Hematologist
Administrative Assistant
Research Fellow
Resident Researcher
Attending Physician and Clinical Investigator
Advanced Clinical Fellow
Instructor, Adult BMT Service
Research Fellow
Visting investigator
Oncology Fellow
Visiting Investigator
Senior Research Scientist
Visiting Investigator