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We leverage large-scale unbiased profiling including genomics, transcriptomics, proteomics to identify candidate oncogenes and proteins that are pathogenetically relevant in lymphoma.

… Kojo S. Elenitoba-Johnson is the Chair of the Department of Pathology and Laboratory Medicine and a physician-scientist. Dr. Elenitoba-Johnson’s research focuses on the role of genomic and proteomic alterations in the pathogenesis of lymphomas. Dr. Megan S. Lim is the Director of the Lymphoma Translational

Computational biologist Ruslan Soldatov develops computational methods to study cell fate decisions and somatic evolution in normal tissues and cancer.

… The Soldatov Lab aims to characterize the mechanisms of cell fate decisions that coordinate tissue function and quantify how distortions of these mechanisms shape the course of cancer evolution. We are broadly interested in using a large-scale data science approach to study questions related to the organization

Optical engineer Milind Rajadhyaksha studies confocal microscopy for the imaging of cancer, technology development, and translational and clinical studies in skin and head and neck cancers.

… I am a mechanical and optical engineer and principal investigator in the Optical Imaging Laboratory in the Dermatology Service. My research focuses on creating novel confocal microscopes and endoscopes for imaging skin and head and neck cancers, and translating this technology to clinical applications

Molecular biologist Thomas Kelly studies regulatory mechanisms that control DNA replication during the cell cycle of eukaryotic cells.

… My long-term interest is to understand how the cellular genome is duplicated during the cell cycle. In the course of growth and division, eukaryotic cells duplicate their genomes with remarkable fidelity. The precision of this process depends in large measure upon stringent regulatory mechanisms that

The Akhmanova laboratory studies cell invasion and migration through tissues, and how it is controlled by surrounding tissue cells.

… Welcome to the Akhmanova lab, where we study how cells penetrate and migrate through tissues in vivo . By combining cutting-edge live imaging, mechano-biological techniques, and theoretical modelling, we aim to uncover the secrets behind these intricate processes. Fig.1 Research methodology and goals

We study mutational processes that drive cancer evolution and treatment resistance.

… The Lee Lab focuses on understanding how cancer genomes evolve under therapeutic pressure, with an emphasis on the origins, structure, and functional impact of genomic rearrangements. By integrating high throughput sequencing data from patient derived samples and experimental models, the lab develops

The Widman Lab within the Digital Oncology Program at MSKCC is using machine learning and genomics to engineer the next-generation of ultrasensitive, highly scalable liquid biopsies for early cancer detection, treatment monitoring, and detection of minimal residual disease (MRD) after surgery for early-stage cancer.

… The Widman lab within the Digital Oncology Program at MSKCC is using machine learning and genomics to engineer the next-generation of ultrasensitive, highly scalable liquid biopsies for early cancer detection, treatment monitoring, and detection of minimal residual disease (MRD) after surgery for early-stage

Physician-scientist James Fagin focuses on the pathogenesis of thyroid cancer and the role of oncogenic kinases.

… The focus of the Fagin lab is to understand the pathogenesis and the biology of thyroid cancers at single cell resolution with the goal of identifying new mechanism-based therapies.  His group has been instrumental in characterizing somatic genetic changes associated with tumor initiation and progression

The Brown Lab studies how the tissue environment shapes immune cell fate and function during early life immune development, inflammation, and cancer.

… At the Brown Lab, we’re studying how signals from the tissue environment shape the fate and function of immune cells and the mechanisms by which the immune system reciprocally regulates tissue homeostasis and host immunity. At the heart of an immune response are dendritic cells, sentinels of the immune

Molecular biologist Prasad Jallepalli studies the mechanisms that ensure accurate chromosome transmission in human cells.

… Our laboratory is interested in how human cells accurately duplicate and transmit their chromosomes during each round of division. Prasad Jallepalli, MD, PhD Member Professor MD, PhD, Johns Hopkins University School of Medicine Achievements Phi Beta Kappa, Harvard University (1992) M.D./Ph.D. Fellow,