Thoracic surgeon Daniela Molena leads clinical trials to improve outcomes for people with esophageal cancers.
At any time Memorial Sloan Kettering Cancer Center is conducting hundreds of clinical trials to improve care for many types of cancer. Use the tool below to browse our clinical trials that are currently enrolling new patients. Each listing explains the purpose of the trial, the trial’s eligibility criteria, and how to get more information.
The list below includes clinical trials for adult cancers. Please visit our pediatric cancer care section to find a pediatric clinical trial.
Researchers want to find the best dose of RMC-9805 to use in people with advanced solid tumors. The people in this study have cancer that keeps growing even with treatment. The tumors also have a mutation (change) in the KRAS gene called G12D.
Researchers want to find the best dose of eganelisib when used alone and with cytarabine to treat leukemia. The people in this study have acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (HR-MDS) that has come back or keeps growing after treatment.          
A standard approach for early-stage rectal cancer is treatment with chemotherapy and radiation therapy followed by surgery. In this study, researchers are comparing two approaches to prevent the need for rectal resection (removal of all or nearly all of the rectum) in people with early rectal cancer: chemotherapy or chemotherapy and radiation with observation or limited surgery (removing only the area with the tumor, not the entire rectum).
To learn more about the purpose of this study and to find out who can join, please click here to visit ClinicalTrials.gov for a full clinical trial description.
Researchers are assessing the use of cobimetinib to treat Langerhans cell histiocytosis (LCH) and other histiocytic disorders. Histiocytic disorders are diseases caused by the abnormal function or buildup of immune cells called histiocytes. Cobimetinib works by blocking the activity of a protein called MEK. This protein leads to the abnormal growth and development of histiocytosis cells.
Cancer and its treatment may affect sexual and reproductive health. The purpose of this study is to evaluate sexual and reproductive health over several years among women age 50 and younger newly diagnosed with breast cancer or lymphoma.
The purpose of this study is to compare three types of support for parents who have experienced the death of a child due to cancer. The study team will assess how these different types of support affect participants' grief and depression symptoms. The three types of support parents may receive are called Meaning-Centered Grief Therapy, Supportive Counseling, and Enhanced Usual Care.
Researchers are seeking the best dose of cirtuvivint to use alone and with ASTX727 for leukemia and myelodysplastic syndromes (MDS). The people in this study have acute myeloid leukemia (AML) or MDS that keeps growing after treatment.
There are unknown factors in our environment and in people's genes that raise the risk of getting pancreatic cancer. To learn about these things, researchers at Memorial Sloan Kettering Cancer Center created a Pancreatic Tumor Registry. This registry includes people with pancreatic cancer, and also people who have a strong family history of this disease.
Treatment for cancer can cause unwanted side effects affecting the skin that may be associated with itching or pain. These side effects may have a direct link to the immune system's response to cancer.
