I am a radiation oncologist who specializes in caring for people with breast cancer, brain tumors, soft tissue sarcoma, skin cancer, and prostate cancer. I am experienced in using advanced treatment techniques, such as brachytherapy, proton therapy, and stereotactic radiation therapy. My experience allows me to offer the people I care for a plan that best suits their diagnosis and treatment goals.
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Radiation oncology is in the middle of a technology revolution. We are creating new tools and techniques that can deliver treatment at a precise level we never could have imagined before. We have also come a long way in understanding the biology of various cancers. All of this means that many people with cancer have better outcomes with fewer side effects. I’m excited to be a part of this progress as a member of the Memorial Sloan Kettering team. MSK combines cutting-edge treatment and research with a history of excellence like no other.
I am heavily involved in clinical and translational research, particularly for breast cancer. Many of the studies I am currently leading are national and multi-institutional. These trials will fundamentally affect how we treat and think about breast cancer. I have also studied accelerated partial breast irradiation. This approach limits radiation to a tumor site, and it cuts down the number of treatment sessions, so patients don’t need to come to the clinic as often. I am also interested in how we can use drugs to make cancer cells more susceptible to the effects of radiation.
Receiving a diagnosis complicates the lives of people with cancer and their caregivers in many unanticipated ways. I experienced this firsthand when my mother was treated for breast cancer. I remember how much my parents valued her doctor’s time and having a personal connection as they navigated the unfamiliar world of hospitals and treatment centers. My experience with my family influences how I care for people with cancer, and I feel privileged to be a part of their lives.
- Clinical Expertise: Radiotherapy for Early and Advanced Breast Cancer; Radiotherapy for Primary and Secondary Brain Tumors; Brachytherapy; Proton Therapy; Stereotactic Cranial and Extracranial Radiotherapy
- Languages Spoken: English; Hindi; Urdu
- Education: MS, Radiological Sciences, Rush University - The Graduate College; MS, Clinical & Translational Science, Rutgers Graduate School of Biomedical Sciences; MD, Aga Khan University Medical College
- Residencies: Rush University Medical Center
- Fellowships: Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School
- Board Certifications: Radiation Oncology
Haffty BG, Harrold E, Khan A, Pathare P, Ward BA, Matloff E, Alvarez-Franco M, Bale AE. (2002). Conservatively Managed Breast Cancer in Young Women: Outcome as a Function of BRCA 1/2 Status. Lancet, 27;359(9316),1471-7.
Khan AJ, Mehta PS, Zusag TW, Bonomi PD , Faber LP, Abrams RA. (2006). Long term disease-free survival resulting from combined modality management of patients presenting with oligometastic, non-small cell lung carcinoma (NSLCL). Radiother Oncol, 81(2),163-7.
Khan AJ, Wall B, Ahlawat S, Green C, Schiff D, Mehnert JM, Goydos JS, Chen S, Haffty BG. (2011). Riluzole Enhances Ionizing Radiation-induced Cytotoxicity in Human Melanoma Cells that Ectopically Express Metabotropic Glutamate Receptor In Vitro and In Vivo. Clinical Cancer Research, 17(7), 1807-14.
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Khan AJ, Vicini FA, Brown S, Haffty BG, Kearney T, Dale R, Lyden M, and Arthur D. (2013) Dosimetric Feasibility and Acute Toxicity in a Prospective Trial of Ultra-short Course Accelerated Partial Breast Irradiation (APBI) using a Multi-Lumen Balloon Brachytherapy Device. Ann Surg Oncol. 20(4):1295-301.
Khan AJ, Rafique R, Zafar W, Shah C, Haffty BG, Vicini F, Jamshed A, Zhao Y. (2017) Nation-Scale Adoption of Shorter Breast Radiotherapy Schedules Can Increase Survival in Resource Constrained Economies: Results from a Markov Chain Analysis. Int J Radiat Oncol Biol Phys. 97(2):287-295. doi: 10.1016/j.ijrobp.2016.10.002. Pubmed PMID: 27986343.
Khan AJ, Poppe M, Goyal S, Kokeny KE, Kearney T, Kirstein L, Toppmeyer D, Moore DF, Chen C, Gaffney DK, Haffty BG. (2017) Hypofractionated Post-Mastectomy Radiation Therapy is Safe and Effective: First Results from a Prospective Phase II Trial. J Clin Oncol. In press.
As home to one of the world’s top cancer research centers, Memorial Sloan Kettering is typically involved in more than 900 clinical trials at a given time. Currently, clinical trials focused on the conditions I treat are enrolling new patients. If you’re interested in joining a clinical trial, click to learn about the trial’s purpose, eligibility criteria, and how to get more information.Learn more
Most major health insurers offer plans that include MSK as one of their in-network providers. If MSK is in-network, it means all our doctors are too. Medicaid and New York State Medicare also provide benefits for care at MSK.Learn more