I am a research scientist with expertise in breast and gynecological cancer high-throughput transcriptomics and genomics. I have employed these techniques to investigate the biology and clinical behavior of specific breast and gynecological cancer subtypes, the similarities between primary breast cancer and their metastatic deposits and between synchronous endometrial and ovarian cancers, and to inform functional studies aiming to define the targetable drivers and molecular markers of response to specific targeted therapies in breast and endometrial cancer cells.
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My current research program focuses on the study of endometrial cancers, the most common gynecologic cancer in developed countries. Benefiting from the unique extensive tissue collections in the Department of Pathology and the state-of-the art facilities at Memorial Sloan Kettering Cancer Center, we are combining traditional pathological techniques with cutting-edge tools for genetic analyses and functional studies. Our aim is to identify biologically relevant subclasses of endometrial cancers and their driving molecular aberrations. The goal of our research is to define how these molecular changes can be exploited to inform us about the optimal therapy for specific patients with endometrial cancer.
In addition, in collaboration with Jorge Reis-Filho’s laboratory, we are characterizing the genetic alterations of rare types of breast cancer for the development of a molecular classification of breast cancers based on their potential therapeutic targets.
- Clinical Expertise: Experimental Pathology; Genomics; Breast and Gynecologic Cancers
- Languages Spoken: English; Dutch; German
- Education: PhD, The Netherlands Cancer Institute, University of Amsterdam (Amsterdam, The Netherlands)
- Fellowships: Lawrence Berkeley National Laboratory (Berkeley, California); Cancer Research UK London Research Institute (London, UK)
As home to one of the world’s top cancer research centers, Memorial Sloan Kettering is typically involved in more than 900 clinical trials at a given time. Currently, clinical trials focused on the conditions I treat are enrolling new patients. If you’re interested in joining a clinical trial, click to learn about the trial’s purpose, eligibility criteria, and how to get more information.Learn more
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