Pictured: Britta Weigelt

Britta Weigelt, PhD

Research Scientist

Titles

Director, Gynecology DMT Research Laboratory

Clinical Expertise

Experimental Pathology; Genomics; Breast and Gynecologic Cancers

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Contact and Location

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About Me

Education

PhD, The Netherlands Cancer Institute, University of Amsterdam (Amsterdam, The Netherlands)

Fellowships

Lawrence Berkeley National Laboratory (Berkeley, California); Cancer Research UK London Research Institute (London, UK)

I am a research scientist with expertise in breast and gynecological cancer high-throughput transcriptomics and genomics. I have employed these techniques to investigate the biology and clinical behavior of specific breast and gynecological cancer subtypes, the similarities between primary breast cancer and their metastatic deposits and between synchronous endometrial and ovarian cancers, and to inform functional studies aiming to define the targetable drivers and molecular markers of response to specific targeted therapies in breast and endometrial cancer cells.

My current research program focuses on the study of endometrial cancers, the most common gynecologic cancer in developed countries. Benefiting from the unique extensive tissue collections in the Department of Pathology and the state-of-the art facilities at Memorial Sloan Kettering Cancer Center, we are combining traditional pathological techniques with cutting-edge tools for genetic analyses and functional studies. Our aim is to identify biologically relevant subclasses of endometrial cancers and their driving molecular aberrations. The goal of our research is to define how these molecular changes can be exploited to inform us about the optimal therapy for specific patients with endometrial cancer.

In addition, in collaboration with Jorge Reis-Filho’s laboratory, we are characterizing the genetic alterations of rare types of breast cancer for the development of a molecular classification of breast cancers based on their potential therapeutic targets.

Colleagues

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Clinical Trials

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Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.

You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.

Research and Publications

View Dr. Weigelt's Lab

Publications on PubMed

Visit PubMed for a full listing of Dr. Weigelt’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.