Britta Weigelt, PhD

My current research program focuses on the study of endometrial cancers, the most common gynecologic cancer in developed countries. Benefiting from the extensive tissue collections in the Department of Pathology and the state-of-the art facilities at Memorial Sloan Kettering Cancer Center, we are combining traditional pathological techniques with cutting-edge tools for genetic analyses and functional studies. Our aim is to identify biologically relevant subclasses of endometrial cancers and their driving molecular aberrations. The goal of our research is to define how these molecular changes can be exploited to inform us about the optimal therapy for specific patients with endometrial cancer.

In addition, in collaboration with Jorge Reis-Filho’s laboratory, we are characterizing the genetic alterations of rare types of breast cancer for the development of a molecular classification of breast cancers based on their potential therapeutic targets.