Charlotte E. Ariyan, MD, PhD

About Me

I am a board-certified general surgeon specializing in surgical oncology with a clinical expertise in melanoma and soft tissue sarcoma. I work closely with the patient and the comprehensive team of physicians to customize treatment plans for each individual.

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In my research, I am investigating new ways to allow the immune system to fight cancer. I am also involved in clinical trials aimed at defining the role of current therapies and improving outcomes through novel new treatments. I am currently the principal investigator (PI) of a Phase II trial investigating the addition of systemic ipilimumab to isolated limb infusion for melanoma in transit disease. I am also the Memorial Sloan Kettering PI of the multi-center MSLT-II trial. This trial randomizes patients with a positive sentinel lymph node to completon lymph node dissection versus ultrasound surveillance of the lymph nodes.

  • Clinical Expertise: Melanoma; Soft Tissue Sarcoma; Merkel Cell Carcinoma
  • Languages Spoken: English; Spanish
  • Education: MD, University of Vermont College of Medicine; PhD, Yale University
  • Residencies: Yale-New Haven Hospital
  • Fellowships: Memorial Sloan Kettering Cancer Center
  • Board Certifications: Surgery

New Patient Appointments

Making an appointment

Call 646-497-9072


Selected Book Chapters
“Salivary gland tumors.” Ariyan S, Narayan D, Ariyan C. In: Plastic Surgery, Volume 5. 2nd ed. Philadelphia: WB Saunders; 2006.

“Surgical management of soft tissue sarcoma: histologic type and grade guide surgical planning and integration of multimodality therapy.” Ariyan C, Singer S. In: Modern Soft Tissue Pathology. New York: Cambridge UP; 2010.

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“Surgical management of soft tissue sarcoma in the geriatric population.” Ariyan C, Brennan M. In: Principles and Practice of Geriatric Surgery. 2nd ed. New York: Springer; 2011.

Visit PubMed for a full listing of Charlotte E. Ariyan’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Clinical Trials

Research is integral to our mission at Memorial Sloan Kettering, and clinical trials help us discover better forms of patient care and treatment. For you, this could mean access to a new therapy or therapy combination. Click to see a list of the trials I’m currently leading.