James J. Harding, MD

About Me

I am a board-certified medical oncologist who specializes in caring for people with liver cancergallbladder cancer, and bile duct cancer, as well as other gastrointestinal cancers. My primary goal is to provide the best possible treatment and individualized care for people with these diseases. I work closely with a team of surgeons, radiation oncologists, and other medical professionals who specialize in the diagnosis and treatment of gastrointestinal cancer.

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In my research, I am trying to find new, effective therapies for gastrointestinal cancer, particularly primary liver and bile duct tumors. For example, I am working on ways to use a patient’s own immune system to fight cancer, which is called immunotherapy. In addition, I am investigating strategies to block specific cellular pathways that cancer uses to grow. I have developed and am leading numerous national and international clinical trials of these new cancer therapies for patients with liver, bile duct cancers, and other solid tumors.

I am also focused on improving how we conduct clinical research with patients and increasing access to clinical trials. To this aim, I am a standing member of the Institutional Review Board, which is the committee that approves all clinical research at Memorial Sloan Kettering. I am also part of several other executive committees aimed at improving the conduct of clinical trials.    

My research and training has been supported by the American Society of Clinical Oncology, the National Comprehensive Cancer Network, the National Institutes of Health, the American Association for Cancer Research, and the Howard Hughes Medical Institute.  My work has been published in the New England Journal of MedicineNature, Nature Medicine, the Journal of Clinical OncologyCancer Discovery, Clinical Cancer Research, and Cancer.

  • Clinical Expertise: Gastrointestinal Malignancies; Liver Cancer (Hepatocellular Carcinoma); Bile Duct Cancers (Cholangiocarcinoma); Gallbladder Cancers; Fibrolamellar Carcinoma; Early Drug Development; Immunotherapy
  • Languages Spoken: English
  • Education: MD, Albert Einstein College of Medicine
  • Residencies: Internal Medicine - NewYork-Presbyterian Hospital
  • Fellowships: Oncology/Hematology - Memorial Sloan Kettering Cancer Center
  • Board Certifications: Internal Medicine; Medical Oncology


Visit PubMed for a full listing of James J. Harding’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Clinical Trials

Research is integral to our mission at Memorial Sloan Kettering, and clinical trials help us discover better forms of patient care and treatment. For you, this could mean access to a new therapy or therapy combination. Click to see a list of the trials I’m currently leading.

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Clinical Trials Led by James J. Harding

Clinical Trials Co-Investigated by James J. Harding


Most major health insurers offer plans that include MSK as one of their in-network providers. If MSK is in-network, it means all our doctors are too. Medicaid and New York State Medicare also provide benefits for care at MSK.

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