James J. Harding, MD

About Me

I am a board-certified medical oncologist who specializes in caring for people with liver cancer, gallbladder cancer, bile duct cancer, pancreatic cancer, and other gastrointestinal cancers. My primary goal is to provide the best possible treatment and individualized care for people with these diseases. I work closely with a team of surgeons, radiation oncologists, and other medical professionals who specialize in the diagnosis and treatment of gastrointestinal cancer.

Plus and Minus IconIcon showing a plus/minus toggle, indicating that the surrounding element can be opened and closed.

In my research, I am trying to find new, effective therapies for gastrointestinal cancer, particularly primary liver and bile duct tumors. I am working on ways to use a patient’s own immune system to fight cancer, which is called immunotherapy. In addition, I am investigating strategies to block specific cellular pathways that cancer uses to grow.

I am also interested in improving how we conduct clinical research with patients and increasing access to clinical trials so we can help people with cancer receive new therapies closer to home. I am a standing member of the Institutional Review Board, the committee that approves all clinical research at Memorial Sloan Kettering.

My research and training has been supported by the American Society of Clinical Oncology, the National Comprehensive Cancer Network, the National Institutes of Health, the American Association for Cancer Research, and the Howard Hughes Medical Institute. In collaboration with basic scientists, my work has been published in the New England Journal of Medicine, Nature Medicine, the Journal of Clinical Oncology, Cancer Discovery, and Cancer.    

  • Clinical Expertise: Gastrointestinal Malignancies; Hepatobiliary Cancers; Pancreatic Cancer; Early Drug Development; Immunotherapy
  • Languages Spoken: English
  • Education: MD, Albert Einstein College of Medicine
  • Residencies: Internal Medicine - NewYork-Presbyterian Hospital
  • Fellowships: Oncology/Hematology - Memorial Sloan Kettering Cancer Center
  • Board Certifications: Internal Medicine; Medical Oncology

New Patient Appointments

Making an appointment

Call 646-497-9053


Visit PubMed for a full listing of James J. Harding’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Clinical Trials

Research is integral to our mission at Memorial Sloan Kettering, and clinical trials help us discover better forms of patient care and treatment. For you, this could mean access to a new therapy or therapy combination. Click to see a list of the trials I’m currently leading.

Plus and Minus IconIcon showing a plus/minus toggle, indicating that the surrounding element can be opened and closed.

Clinical Trials Led by James J. Harding

Clinical Trials Co-Investigated by James J. Harding


Most major health insurers offer plans that include MSK as one of their in-network providers. If MSK is in-network, it means all our doctors are too. Medicaid and New York State Medicare also provide benefits for care at MSK.

Learn more