Mary Louise Keohan, MD

About Me

I am a medical oncologist who cares for adults with a very rare cancer known as soft tissue sarcoma. These tumors are notoriously difficult to treat because they begin in the connective tissues — such as fat, muscles, nerves, tendons, and blood and lymph vessels — that surround and support other parts of the body.

My fellow medical oncologists and I work alongside a broader disease management team that includes pathologists, surgeons, and radiation oncologists. Together, we create an individualized treatment plan for each patient, based on the need to preserve limb and organ function as best we can. Chemotherapy is often used as part of treatment, either before surgery to shrink a larger tumor or after surgery to kill any remaining cells that remain in the body. As a leader in the treatment of these complicated diseases, we also seek ways to refine and enhance therapy alternatives through various clinical research trials.

I am grateful to receive research funding from a number of sarcoma-related philanthropic organizations, including the Liddy Shriver Ewing’s Sarcoma Fund, the Alan Rosenthal Research Fund in Hemangiopericytoma, and the Dorcas Casey Fund for Sarcoma. From this research, I have published more than 60 journal articles, reviews, and abstracts.

Outside of Memorial Sloan Kettering, I am active in a number of our specialty’s key medical groups, including the American Society of Clinical Oncology, the Connective Tissue Sarcoma Society, and the Sarcoma Alliance for Research Through Collaboration.

  • Clinical Expertise: Sarcomas of Soft Tissue and Bone; New Investigational Therapies; Gastrointestinal Cancers
  • Languages Spoken: English
  • Education: MD, St. George's University of Medicine
  • Residencies: Internal Medicine - University of Medicine and Dentistry of New Jersey
  • Fellowships: Medicine - Columbia University
  • Board Certifications: Internal Medicine; Medical Oncology


Most major health insurers offer plans that include MSK as one of their in-network providers. If MSK is in-network, it means all our doctors are too. Medicaid and New York State Medicare also provide benefits for care at MSK.

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Clinical Trials

As home to one of the world’s top cancer research centers, Memorial Sloan Kettering is typically involved in more than 900 clinical trials at a given time. Currently, clinical trials focused on the conditions I treat are enrolling new patients. If you’re interested in joining a clinical trial, click to learn about the trial’s purpose, eligibility criteria, and how to get more information.

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