Richard J. O'Reilly, MD -- Chair, Department of Pediatrics; Chief, Pediatric Bone Marrow Transplant Service; Claire L. Tow Chair in Pediatric Oncology Research

Richard J. O'Reilly, MD

Pediatric Oncology

Titles

Claire L. Tow Chair in Pediatric Oncology Research

Clinical Expertise

Pediatric Oncology; Allogeneic and Autologous Bone Marrow and Peripheral Blood Stem Cell Transplantation; Congenital and Acquired Diseases of Hematopoiesis and Immunity

New Patient Appointments

Scheduling a visit is easy. Click below or call us to get started.

Accepted Insurance Providers

Dr. O'Reilly accepts the following list of insurance providers. Select your insurance provider to see more details.

Aetna

Memorial Sloan Kettering is an in-network provider with Aetna HMO, POS, and PPO plans. Aetna does not include us in any of the plans you can purchase through the insurance exchanges or through Medicare. Please ask your insurance if you need a one-time referral.

Blue Cross Blue Shield

In New York State

Memorial Sloan Kettering is an in-network provider with Empire Blue Cross Blue Shield (Wellpoint) of New York HMO, EPO, PPO, and POS plans, with the following exceptions:

  • Empire Blue Cross Blue Shield does not include us in any of the plans you can buy through the insurance exchanges.
  • Memorial Sloan Kettering is not an in-network provider for Empire's Medicare Managed Care plan known as Mediblue).
  • The Empire Indemnity Plan provides limited coverage for our services.

Memorial Sloan Kettering is a designated Center of Excellence by Blue Cross Blue Shield.

In New Jersey

Memorial Sloan Kettering is an in-network provider with some Horizon Blue Cross Blue Shield of New Jersey plans for individuals, families, and small businesses. For example, the PPO plan is in-network with our Manhattan locations.

Horizon Blue Cross HMO is only in-network with our Basking Ridge, Bergen and Monmouth locations. It does not allow access to our Manhattan facilities.

Horizon Blue Cross PPO is in network with our Basking Ridge, Bergen, Monmouth and Manhattan locations.

OMNIA Plans: Tier I EPO based plan policy is only in-network with our Basking Ridge, Bergen and Monmouth locations and does not allow access to our Manhattan sites. Tier II EPO is only in-network with our Manhattan sites if it is a blue-card plan (there would be a suitcase logo indicating PPO on the front of the card).

Other plans may only be in-network at our Basking Ridge, Bergen or Monmouth locations.

Outside New York State and New Jersey

Some, but not all, Blue Cross Blue Shield plans outside of New York and New Jersey include Memorial Sloan Kettering as an in-network provider. Contact your insurance to find out if your plan provides in-network access to Memorial Sloan Kettering.

CIGNA

Memorial Sloan Kettering is an in-network provider with CIGNA's HMO, POS, and PPO plans. CIGNA does not include us in any of the plans you can buy through the insurance exchanges.

  • If you are a New York State resident: Please ask your insurance if you need a one-time referral.
  • If you live outside of New York State: Please ask your insurance if you have in-network access to Memorial Sloan Kettering.

Memorial Sloan Kettering is a designated Center of Excellence by Blue Cross Blue Shield.

EmblemHealth (including GHI, HIP, ConnectiCare, and Vytra)

Memorial Sloan Kettering is an in-network provider with EmblemHealth’s PPO, EPO, POS, and HMO plans as well as their Enhanced Care Prime Network, which supports Medicaid Managed Care and Child Health Plus and Medicare plans. Memorial Sloan Kettering is also in-network with the New York State Essential Emblem Health plan, which can be purchased on the insurance exchange. Emblem Health does not include us in any of its Medicare plans or in any of its Select Care network plans. You must bring a referral from your Emblem primary care doctor to your first appointment.

Empire Blue Cross Blue Shield Health Plus

Formerly known as Health Plus Amerigroup, Empire Blue Cross Blue Shield Health Plus is an in-network provider with Memorial Sloan Kettering. You will need a one-time referral from your primary care doctor.

Health Insurance Exchanges

We understand that there may be many complexities involved with insurance coverage purchased through the health exchange network of the Affordable Care Act. We're here to help. If you have questions about how your care will be covered by an insurance provider, or need help navigating a change in coverage, please call us at 646-227-3378; if you are not a resident of New York, you can call us at 866-248-1274. Our team is here to listen to your concerns and assist you in any way we can. We want our care to be as accessible and affordable for as many people as possible.

HealthSmart

Memorial Sloan Kettering is an in-network provider with HealthSmart’s Accel, HSPC, and HPO networks.

Humana

Memorial Sloan Kettering is a designated Center of Excellence by Humana.

Interlink Health Services

Memorial Sloan Kettering is a designated Center of Excellence by Interlink Health Services.

Lifetrac

Memorial Sloan Kettering is a designated Center of Excellence by Lifetrac.

MagnaCare

Memorial Sloan Kettering is an in-network provider for all MagnaCare health plans except those products you can buy through the insurance exchanges.

Medicaid

New York State Medicaid covers physician and hospital services at Memorial Sloan Kettering. Patients are responsible for co-payments.

We also have contractual relationships involving Medicaid Managed Care plans. MSK is an in-network provider with Medicaid NY Emblem Health (formerly known as HIP) and Medicaid NY Empire Blue Cross Blue Shield HealthPlus (formerly known as Amerigroup). You will need a one-time referral from your primary care doctor.

Medicare

Hospital and physician services at Memorial Sloan Kettering are covered by standard Medicare insurance. You are responsible for co-insurance and deductible costs. 

In New York: Memorial Sloan Kettering’s New York locations are in-network with the Emblem Medicare Advantage Plans.

In New Jersey: Memorial Sloan Kettering’s  New Jersey locations in Basking Ridge, Bergen and Monmouth are in-network with the Horizon Medicare Advantage Plan. This plan is not accepted for care provided at MSK’s New York locations.

If you are enrolled in any other Medicare Advantage plan, please contact your insurance carrier to determine your benefits and coverage at Memorial Sloan Kettering since your access may be limited.

Multiplan/Beech Street/PHCS

Memorial Sloan Kettering is an in-network provider with some Multiplan/Beech Street/PHCS plans. Contact your insurance carrier to find out if your plan provides in-network access to Memorial Sloan Kettering.

Memorial Sloan Kettering is a designated Center of Excellence by Multiplan.

Multiple Insurance Plans

If you are covered by more than one insurance plan, you will want to determine your benefits from both plans. First, you need to determine which one is your primary insurance provider by contacting your employee benefits office or your insurance carriers. After you find out which is your primary insurance provider, you should then contact your insurance carrier to determine if you have access to Memorial Sloan Kettering.

MVP

Memorial Sloan Kettering is an in-network provider with some MVP plans. Contact your insurance carrier to find out if your plan provides in-network access to Memorial Sloan Kettering.

New York State Employee Health Insurance Plan (Empire Plan)

Memorial Sloan Kettering is an in-network provider for New York State employees who have enrolled in UnitedHealthcare's Cancer Resource Services. If you have the Empire Plan, you should call Cancer Resources Services at 866-936-6002 to verify and enroll in this coverage.

Oscar

Memorial Sloan Kettering is in-network with Oscar's Circle Plus Network, a part of its Small Group Broad line that is offered only to select small business groups. Oscar does not include Memorial Sloan Kettering as an in-network provider for any of its individual plans. Please confirm eligibility with your insurance carrier.

Other Coverage Options

We have agreements with several insurance companies that may provide additional coverage for cancer patients. These benefit programs include:

  • AXA Assistance USA
  • Beech Street
  • Integrated Health Plans
  • National Health Administrators
  • National Preferred Provider Network
  • UnitedHealthcare's Cancer Resource Services
  • United Resource Network
  • Veterans Choice Program
Oxford

Memorial Sloan Kettering is an in-network provider with Oxford’s Freedom and Liberty plans as well as the Metro Plan (which is only offered to small business groups and no longer offered as individual plans). Please confirm with your insurance if you need a one-time referral. Note: Oxford's Medicare Managed Care plan — Secure Horizon — does not include Memorial Sloan Kettering as an in-network provider. Oxford does not include us in any of the plans you can buy through the insurance exchanges.

QualCare

Memorial Sloan Kettering is an in-network provider with QualCare's PPO and HMO/POS network.

Specialty Care Management

Memorial Sloan Kettering is a designated Center of Excellence by Specialty Care Management.

TRICARE

Hospital and physician services at Memorial Sloan Kettering are covered by TRICARE. You are responsible for co-insurance and deductible costs.

UnitedHealthcare

Memorial Sloan Kettering is an in-network provider with UnitedHealthCare's HMO, POS, and PPO plans. Please confirm with your insurance if a one-time referral is needed.

UnitedHealthCare's Medicare Managed Care plan does not include Memorial Sloan Kettering as an in-network provider.

United does not include us in any of the plans you can buy through the insurance exchanges.

Memorial Sloan Kettering is a designated Center of Excellence by UnitedHealthcare.

World Trade Center Health Program

Memorial Sloan Kettering is an in-network provider with the World Trade Center Health Program.

Contact and Location

Find a Convenient Location

Memorial Sloan Kettering has locations throughout New York City, Long Island, New Jersey, and Westchester. These locations offers many services, including screening, chemotherapy, and medical testing.

See all locations

About Me

Education

MD, University of Rochester School of Medicine

Residencies

Pediatrics - Children's Hospital Medical Center

Fellowships

Infectious Disease - Children's Hospital Medical Center/Beth Israel Hospital

Board Certifications

Pediatrics

As former Chair of the Department of Pediatrics, I oversaw all aspects of the clinical, medical education, and research endeavors the department is privileged to provide. My clinical expertise is in bone marrow transplantation and the treatment of children with congenital and acquired immunological deficiencies. I have particular expertise in treating genetic diseases that impair hematopoiesis — the formation of blood cells — as well as pediatric leukemias. I am also an authority on transplantation immunology and cellular therapies.

I’ve always been fascinated by the immunology of transplantation and our ability to use this approach to cure diseases. I was involved in the first transplant of bone marrow from an unrelated donor to a patient in 1973. This opened the possibility of a transplant to the majority of patients who lack a matched brother or sister. Since then, we have greatly refined this approach. In fact most of the transplants we perform are now from unrelated donors.

I also conduct laboratory and clinical research, and have led national studies of new therapies for children with genetic immunodeficiencies and both adults and children with leukemia and other life-threatening blood diseases. I and my colleagues developed and introduced methods for removing T cells from the donor’s transplant. (T cells are the white blood cells that can attack the tissues of the patient and cause a complication called graft-versus-host disease [GvHD]). This approach has proven to be an effective way to prevent GvHD, and has allowed us to transplant marrow from genetically half-matched donors, such as a mother or father, without causing severe or fatal GvHD. We’ve also developed and introduced in clinical trial, new immune cell therapies to manage other potential complications of transplantation, such as Epstein-Barr-virus lymphomas and cytomegalovirus infections. Today there is no more “boy in the bubble,” thanks to the advances we’ve made in bone marrow transplantation.

My fellow scientists and I are now developing cellular therapies that could be used to enhance the resistance of bone marrow transplant recipients to not only serious infections but also their underlying cancers. We’re aiming to create novel systems to elicit an immune response in the patient against infectious organisms or residual cancer cells.

I am privileged to work with a dedicated and experienced team of professionals who have the capacity to assess clinical challenges and develop innovative solutions. We share a passion for delivering good medicine. We’ve also developed support systems for patients and their families that are second to none.

I have shared my experience and knowledge with fellows and residents, many of whom have gone on to establish bone marrow transplant programs at institutions around the world. I am past-President and currently a member of the Board of the Damon Runyon-Walter Winchell Cancer Fund, and on the Board of the Children’s Oncology Society of New York, which runs the local Ronald McDonald House. I have won several awards for my work, including honors from the American Society of Clinical Oncology, the Society of Translational Oncology, the American Society for Blood and Marrow Transplantation, and Leiden University in The Netherlands.

Awards and Honors

  • New York Magazine Top Doctors (2002-2016)

Colleagues

Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.

Clinical Trials

Find a Clinical Trial for You

Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.

You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.

Search clinical trials

Research and Publications

View Dr. O'Reilly's Lab

Dinsmore R, Kirkpatrick D, Flomenberg N, et al. Allogeneic bone marrow transplantation for patients with acute lymphoblastic leukemia. Blood 1983; 62 :381

Shank B, Chu FC, Dinsmore R, et al. Hyperfractionated total body irradiation for bone marrow transplantation. Results in seventy leukemia patients with allogeneic transplants. Int J Radiat Oncol Biol Phys 1983; 9 :1607

Brochstein JA, Kernan NA, Groshen S, et al. Allogeneic bone marrow transplantation after hyperfractionated total-body irradiation and cyclophosphamide in children with acute leukemia. N Engl J Med 1987; 317 :1618

Papadopoulos EB, Carabasi MH, Castro-Malaspina H, et al. T-cell-depleted allogeneic bone marrow transplantation as postremission therapy for acute myelogenous leukemia: freedom from relapse in the absence of graft-versus-host disease. Blood 1998 Feb 1;91(3):1083-90 1998; 91 :1083

Boulad F, Steinherz P, Reyes B, et al. Allogeneic bone marrow transplantation versus chemotherapy for the treatment of childhood acute lymphoblastic leukemia in second remission: a single-institution study. J Clin Oncol 1999; 17 :197

Walters MC, Sullivan KM, O’Reilly RJ, et al. Bone marrow transplantation for thalassemia. The USA experience.. Am J Pediatr Hematol Oncol 1994; 16 :11

Boulad F, Giardina P, Gillio A, et al. Bone marrow transplantation for homozygous beta-thalassemia. The Memorial Sloan Kettering Cancer Center experience. Ann N Y Acad Sci 1998; 850 :498

Gillio AP, Boulad F, Small TN, et al. Comparison of long-term outcome of children with severe aplastic anemia treated with immunosuppression versus bone marrow transplantation. Biol Blood Marrow Transplant 1997; 3 :18

O’Reilly RJ, Dupont B, Pahwa S, et al. Reconstitution in severe combined immunodeficiency by transplantation of marrow from an unrelated donor. N Engl J Med 1977; 297 :1311

O’Reilly RJ, Kapoor N, Pollack M, et al. Reconstitution of immunologic function in a patient with severe combined immunodeficiency following transplantation of marrow from an HLA-A,B,C nonidentical but MLC-compatible paternal donor. Transplant Proc 1979; 11 :1934

Reisner Y, Kapoor N, Kirkpatrick D, et al. Transplantation for severe combined immunodeficiency with HLA-A,B,D,DR incompatible parental marrow cells fractionated by soybean agglutinin and sheep red blood cells. Blood 1983; 61 :341

O’Reilly RJ, Keever CA, Small TN, et al. The use of HLA-non-identical T-cell-depleted marrow transplants for correction of severe combined immunodeficiency disease. Immunodefic Rev 1989; 1 :273

Brochstein JA, Gillio AP, Ruggiero M, et al. Marrow transplantation from human leukocyte antigen-identical or haploidentical donors for correction of Wiskott-Aldrich syndrome. J Pediatr 1991; 119 :907

Castro-Malaspina H, Childs B, Laver J, et al. Hyperfractionated total lymphoid irradiation and cyclophosphamide for preparation of previously transfused patients undergoing HLA-identical marrow transplantation for severe aplastic anemia. Int J Radiat Oncol Biol Phys 1994; 29 :847

 

Publications on PubMed

Visit PubMed for a full listing of Dr. O'Reilly’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.

See all on PubMed