Memorial Sloan Kettering medical oncologist Santosha Vardhana

Santosha Vardhana, MD, PhD

Lymphoma Specialist


Assistant Attending Physician

Clinical Expertise

Hodgkin lymphoma; Non-Hodgkin Lymphoma


Contact and Location

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Memorial Sloan Kettering has locations throughout New York City, Long Island, New Jersey, and Westchester. These locations offer many services, including screening, chemotherapy, and medical testing.

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About Me


PhD, New York University School of Medicine; MD, New York University School of Medicine


Internal Medicine – NewYork-Presbyterian Hospital/Weill Cornell Medical Center


Medical Oncology – Memorial Sloan Kettering Cancer Center

Board Certifications

Internal Medicine; Medical Oncology

I am a medical oncologist who specializes in treating and researching Hodgkin and non-Hodgkin lymphoma. I provide comprehensive care for people who have been admitted to Memorial Hospital, Memorial Sloan Kettering’s inpatient facility.

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My research is focused on how we can harness the body’s immune system to attack cancer. I am particularly interested in exploring how changes in metabolic pathways affect the immune system’s ability to recognize and eliminate cancer cells. As a scientist, I draw inspiration from the courage of my patients and their determination to better understand the disease they are facing and, ultimately, develop new strategies to help them.

Patients often have a great deal of anxiety about what their future holds. It can be difficult to imagine what life will be like when they leave the hospital. I hope to help my patients understand what to expect in both the short term and long term by clearly explaining their disease, how it occurs, and how we can treat it. I work closely with their outpatient doctors to ensure that we are approaching their treatment as a united front.

Awards and Honors

  • Parker Fellow, Parker Institute for Cancer Immunotherapy (2017)
  • Young Investigator Award, American Society of Clinical Oncology (2016)
  • Fellowship in Clinical Lymphoma Research, American Association of Cancer Research (2016)


Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.

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Clinical Trials

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Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.

You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.

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Research and Publications

View Dr. Vardhana's Lab

Vardhana S, Choudhuri K, Varma R, Dustin ML. Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster. Immunity. 2010 Apr 23;32(4):531-40.

Kumari S, Vardhana S, Cammer M, Curado S, Santos L, Sheetz MP, Dustin ML. T Lymphocyte Myosin IIA is Required for Maturation of the Immunological Synapse. Front Immunol. 2012;3:230. Doi: 10.3389/fimmu.2012.00230.

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Vardhana S, Sauter CS, Matasar MJ, Zelenetz AD, Galasso N, Woo KM, Zhang Z, Moskowitz CH. Outcomes of primary refractory diffuse large B-cell lymphoma (DLBCL) treated with salvage chemotherapy and intention to transplant in the rituximab era. Br J Haematol. 2016 Dec 16.

Fooksman DR, Vardhana S, Vasiliver-Shamis G, Liese J, Blair DA, Waite J, Sacristán C, Victora GD, Zanin-Zhorov A, Dustin ML. Functional anatomy of T cell activation and synapse formation. Annu Rev Immunol. 2010;28:79-105. Doi: 10.1146/annurev-immunol-030409-101308.

Vardhana S, Younes A. The immune microenvironment in Hodgkin lymphoma: T cells, B cells, and immune checkpoints. Haematologica. 2016 Jul; 101(7): 794-802.

Publications on PubMed

Visit PubMed for a full listing of Dr. Vardhana’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.

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Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Santosha Vardhana discloses the following relationships and financial interests:

  • ADC Therapeutics
    Provision of Services
  • Immunai Inc.
    Provision of Services

If you’re a patient at MSK and would like more information about your doctor’s external relationships, please talk with your doctor.

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2021 through disclosure submission in spring 2022). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].

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