Clinical Updates & Insights

About a third of patients with metastatic breast cancer don’t respond well to the standard anti-estrogen therapies; to find ways to better treat those patients, Memorial Sloan Kettering Cancer Center is studying three new selective estrogen receptor down-regulators (SERDs) in clinical trials.

Sacral neuromodulation has already helped patients with benignly caused fecal incontinence – can it do the same for rectal cancer patients following sphincter-preserving surgery?

Two intraperitoneal chemotherapy approaches are being compared for effectiveness and toxicity in Memorial Sloan Kettering Cancer Center’s phase II clinical trial, which continues to enroll cytoreductive cancer surgery patients with isolated peritoneal metastasis.

The evolution of the surgical management of regional lymph nodes in patients with melanoma is an extraordinary lesson in the importance of humility and open-mindedness for academic surgeons.