Search by keywords: and/or Search by cancer type: Thoracic-Lung Cancer [5]--Lung Cancer, Non-Small Cell [74]---Lung Adenocarcinoma [2]---Other [3]--Lung Cancer, Small Cell [8]---Other [1] Narrow your choices Trial phase: - Any -Pilot (small research study)Phase I (phase 1)Phase I/II (phases 1 and 2 combined)Phase II (phase 2)Phase II/III (phases 2 and 3 combined)Phase III (phase 3)Phase IV (phase 4)N/APhase III/IV (phases 3 and 4 combined)Phase 0 (very small research study) Reset 83 Clinical Trials found A Phase 2 Study of Zipalertinib in People With Advanced Non-Small Cell Lung Cancer The purpose of this study is to see how well zipalertinib works to treat advanced lung cancer. The people in this study have non-small cell lung cancer (NSCLC) that has spread. The cancer also has a mutation (change) in the EGFR gene. When people have an EGFR mutation, the EGFR protein on their cells can trigger cancer growth. New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau A Phase 3 Study Assessing the Addition of High-Dose, Targeted Radiation to the Usual Treatment for Inoperable Non-Small Cell Lung Cancer Researchers want to see if giving additional radiation therapy to standard treatment helps people with lung cancer to live longer. The people in this study have non-small cell lung cancer (NSCLC) that cannot be removed with surgery (inoperable cancer). The standard treatment includes image-guided radiation therapy (IGRT), chemotherapy, and immunotherapy with durvalumab. New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau A Phase 3 Study Comparing Neladalkib (NVL-655) With Alectinib in People With Advanced Non-Small Cell Lung Cancer In addition, their cancers have a fusion (change) in the ALK gene. The fusion gene makes a protein that promotes cancer growth and survival. This type of cancer is called ALK-positive NSCLC. New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau A Phase 3 Study Comparing Proton Craniospinal Radiation Therapy With the Usual Radiation Therapy for Leptomeningeal Metastasis Breast cancer and non-small cell lung cancer (NSCLC) can spread to the cerebrospinal fluid-filled space around the brain and spinal cord. This is called leptomeningeal metastasis (LM). The effects of LM on the nervous system can be very serious. New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau A Phase 3 Study of Dato-DXd With or Without Osimertinib Versus Chemotherapy for People With Non-Small Cell Lung Cancer If you join this study, you will be randomly assigned to get one of these treatments: New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau A Phase 3 Study of Ivonescimab Versus Pembrolizumab Immunotherapy for the Initial Treatment of Metastatic Non-Small Cell Lung Cancer Researchers are comparing ivonescimab with pembrolizumab immunotherapy for the initial treatment of advanced lung cancer. The people in this study have non-small cell lung cancer (NSCLC) that has metastasized (spread). New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau A Phase 3 Study of LY3537982, Pembrolizumab Immunotherapy, and Other Standard Therapies in People With Advanced Non-Small Cell Lung Cancer Researchers are doing this study to see if giving LY3537982 with standard lung cancer drugs is safe and works well. The people in this study have non-small cell lung cancer that has spread. In addition, their cancers have a gene mutation (change) called KRASG12C, which can cause cancer cells to grow. New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau A Phase 3 Study of Olomorasib Plus Immunotherapy in People With Stage 2 or 3 Non-Small Cell Lung Cancer In addition, their cancers have a mutation (change) in the G12C location of the KRAS gene. Olomorasib may help slow or stop the growth of cancers with KRAS G12C mutations. It is taken orally (by mouth). New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau A Phase 3 Study of RMC-6236 Versus Docetaxel in People With Advanced Non-Small Cell Lung Cancer Researchers are comparing RMC-6236 with docetaxel for the treatment of lung cancer. The people in this study have non-small cell lung cancer (NSCLC) that has spread beyond its original location. In addition, their tumors have a mutation (change) in the RAS gene. New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau A Phase 3 Study of Taletrectinib versus Placebo in People with Non-Small Cell Lung Cancer After Complete Tumor Removal Researchers are comparing taletrectinib with a placebo (inactive drug) in people with non-small cell lung cancer (NSCLC). The people in this study have stage 1B-3A NSCLC that has a ROS1 gene fusion. They have had the tumor completely removed with surgery. 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