Ewing Sarcoma Clinical Trials & Research

Pictured: Tanya Trippett
Pediatric oncologist and clinical researcher Tanya Trippett meets with a family.

MSK Kids offers a range of clinical trials evaluating new approaches for children with Ewing sarcoma. Trials are available for newly diagnosed children and for those whose cancer has continued growing or come back after treatment.  

Some of our clinical trials are evaluating new drugs. Others are assessing existing drugs and drug combinations used in adults with cancer that may be useful in young people with Ewing sarcoma. For example, our investigators learned through a clinical trial that irinotecan (Camptosar®) and temozolomide (Temodar®) — drugs already used to treat colorectal cancer and brain cancer in adults — are effective against Ewing sarcoma that come backs after standard treatment. Today, these two medications are now part of the arsenal of standard therapies we use to treat newly diagnosed Ewing sarcoma.

Your child’s care team will let you know if your child can participate in a clinical trial. The decision to enroll is entirely voluntary. The study team will explain the benefits and risks of the study to you so you can make an informed decision.

and/or
3 Clinical Trials found
In this study, researchers are assessing the safety of the drug lurbinectedin in young people with solid tumors. In the first part, they will find the highest dose of lurbinectedin to use safely in children with solid tumors. If your child joins, this is the part of the study they will be in.
Researchers in this study want to find the best dose of lurbinectedin to treat cancer in children and adults. They also want to see how well this drug works. The people in this study have Ewing sarcoma or other solid tumors that keep growing after treatment. In addition, their cancers contain a genetic change called a FET fusion.
To learn more about the purpose of this study and to find out who can join, please click here to visit ClinicalTrials.gov for a full clinical trial description.