Clinical Trials & Research for Children with Kidney Tumors

At MSK Kids, your child may be able to take part in a clinical trial, also known as a clinical research study. In a clinical trial, doctors evaluate a new treatment or combination of treatments to see if they are more effective than current treatments. Nearly every pediatric kidney tumor treatment used today exists because of a clinical trial. 

Our patients have access to many of the latest clinical trials, some of which are available only at MSK Kids. We also participate in many nationwide clinical trials as a founding member of the Children’s Oncology Group, as the coordinating center and co-founder of the Pediatric Oncology Experimental Therapeutics Investigators’ Consortium, and through other clinical trial networks across the United States.

The decision to have your child take part in a clinical trial is entirely up to you and your family. Regardless of whether your child receives standard kidney tumor treatment or treatment through a clinical trial, he or she will benefit from MSK Kids’ ongoing commitment to providing the best care for children.

Learn more about MSK Kids’ current clinical trials for pediatric kidney tumors.

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4 Clinical Trials found
Researchers want to see how well selinexor works in people with Wilms' tumor and other solid tumors. The people in this study are children and adults with tumors that depend on a protein called XPO1. XPO1 helps cancer cells grow by getting rid of proteins that can cause those cells to die (tumor suppressor proteins).
The purpose of this study is to find the highest dose of the investigational drug codrituzumab that can be given safely in children and young adults with solid tumors that came back or continued to grow despite treatment. Codrituzumab works by targeting a protein called GPC3, which can drive the growth of some forms of cancer that affect children and young adults. It is given intravenously (by vein).
This study is evaluating the safety and effectiveness of combination chemotherapy, surgery, and radiation therapy in children and young adults with newly diagnosed stage II-IV diffuse anaplastic Wilms' tumors (DAWT) or favorable histology Wilms' tumors (FHWT) that have come back (relapsed).
Wilms tumor the most common type of kidney cancer in children. Favorable tissue (histology) Wilms tumors (FHWT) are the most common subtype.