Recent MSK Discoveries & Advances

Memorial Sloan Kettering researchers are relentlessly exploring every aspect of cancer — from basic investigations of cells and molecules to clinical trials of new treatments and population-wide studies of the disease. While our core mission is to translate this knowledge into new strategies to control cancer, many of our investigators are also making scientific progress against other diseases and conditions.

Below are some examples of discoveries and advances that recently were made in our laboratories and clinics, and featured in our news stories.

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382 News Items found
Chromosomes from a human male
In the Lab
How Small Chromosomes Compete with Big Ones for a Cell’s Attention

During meiosis, small chromosomes risk being lost in the shuffle. Here’s how they hold their own.
Fluorescent image of mouse prostate gland
In the Lab
New Discovery Explains How the Prostate Gland Regenerates Itself

Androgen-deprivation therapy, a mainstay of prostate cancer treatment, may give prostate cells new growth abilities, scientists at Memorial Sloan Kettering have found.
Four dogs wearing blue bandanas are held on leashes in a hallway at Memorial Hospital. Three handlers are seen only from the waist down.
Feature
Top Dogs: Meet MSK’s Four-Legged Volunteers

The Caring Canines program at Memorial Sloan Kettering has been going strong for more than 12 years.
An illustration of a samurai riding a horse along a strand of RNA. The samurai’s sword is changing the letter A to the letter I.
In the Lab
Novel Tool Enables Study of Rare Acute Myeloid Leukemia Stem Cells

MSK investigators have used a lab tool originally developed to study fly nerve cells to uncover new findings about acute myeloid leukemia.
Bacteroides bacteria under the microscope
In the Lab
Research Uncovers Details about How Gut Microbes Influence the Immune System

Investigators have shown how gut microbes promote the formation of a type of immune cell called regulatory T cells.
Cancer biologist Scott Lowe
In the Lab
Drug Combination Could Boost the Effectiveness of Immunotherapy against Pancreatic Cancer

Studies conducted in mice reveal a potential way to breach the defenses of pancreatic cancer tumors.
The latest results come from a team of MSK physicians and scientists (from left to right): Bob Li, Hai-Yan Tu, Mackenzie Myers, Flavia Michelini, Emiliano Cocco, Sandra Misale, and Maurizio Scaltriti
In the Clinic
Back-to-Back Studies Support the Use of HER2-Targeted Therapies in Multiple Cancers

Results from a clinical trial and animal studies provide support for targeting the HER2 protein in multiple cancer types.
blood tube laying atop DNA sequence
In the Clinic
Liquid Biopsy Can Guide Treatment for Women with Metastatic Breast Cancer

By identifying mutations found in a person’s cancer, this blood test can help doctors tailor treatments to those most likely to benefit.
black and white image of cells under a microscope
In the Lab
Researchers Discover Stem Cells That May Drive Aggressive Behavior in Glioblastoma

Researchers have discovered uncanny similarities between cells found in brain tumors and a type of stem cell that’s important for building the brain during fetal development.
Surgeon-scientist Vinod Balachandran
In the Lab
What’s Next in Immunotherapy for Pancreatic Cancer? New Immune Cell Type May Be Key

Researchers find a potential new route to making immunotherapy work better in pancreatic cancers and possibly others.