The Charles Sawyers Lab: Featured News

Lineage plasticity in prostate cancer depends on JAK/STAT inflammatory signaling
Resistance to molecularly targeted therapies is often due to mutations in the drug target, but there is growing recognition of other modes of tumor esc...
Charles Sawyers in his lab
A New Approach in Prostate Cancer: Targeting the Cells Surrounding the Tumor
Scientists have found a protein that empowers prostate tumors to resist hormone therapy.
Courtesy of the AACR
MSK Experts Featured at the AACR Virtual Annual Meeting I
Thousands of oncology experts from around the world will tune in April 27 and 28 for the American Association for Cancer Research’s (AACR) virtual annual meeting I. The meeting is the first of two virtual sessions, with clinical trial plenary sessions, clinical trial poster sessions, several minisymposia, and more. The AACR virtual annual meeting II will be held June 22 through 24.
In the Lab
Fluorescent image of mouse prostate gland
New Discovery Explains How the Prostate Gland Regenerates Itself
Androgen-deprivation therapy, a mainstay of prostate cancer treatment, may give prostate cells new growth abilities, scientists at Memorial Sloan Kettering have found.
In the Lab
Blue cells on a black background
Scientists Create the First Human-Tumor-Derived Model for Studying Rectal Cancer
Scientists at Memorial Sloan Kettering have created a model of rectal cancer using human-tumor-derived organoids.
In the Lab
MSK cancer researchers Elizabeth Adams, Charles Sawyers, and Rohit Bose
Researchers Unravel the Biology of a Distinct Prostate Cancer Subtype
Mutations in a gene called FOXA1 are responsible for a distinct class of prostate cancer tumors, MSK researchers have found.
In the Clinic
A yellow molecular model of the androgen receptor on brown background
An Unlikely Treatment for Triple-Negative Breast Cancer: Prostate Cancer Drugs
Doctors are developing treatment strategies that target the androgen receptor, which is found in many triple-negative breast cancers.
Image of As, Ts, Cs, and Gs representing genetic code
AACR Project GENIE Seeks to Advance Cancer Treatment
Eight leading cancer centers are coming together to share genomic sequencing data, in the hope of making faster progress in curing cancer.
In the News
Vice President Joe Biden addressed members of the American Association for Cancer Research on Wednesday in New Orleans.
At #AACR16, Vice President Biden Unveils ‘Moonshot’ Goal: A Decade’s Worth of Progress in Five Years
The 2016 annual meeting of the American Association for Cancer Research (AACR) ended with a visit from the Vice President.