Dr. Sawyers is investigating the signaling pathways that drive the growth of cancer cells, with an eye toward designing new treatment options for patients with chronic myeloid leukemia, prostate cancer, and glioblastoma.
Charles L. Sawyers, MD
Investigator, Howard Hughes Medical Institute; Marie-Josée and Henry R. Kravis Chair in Human Oncology and Pathogenesis; Chair, Human Oncology and Pathogenesis Program
Professor
Research Focus
Human Oncology and Pathogenesis Program Chair Charles Sawyers develops molecularly targeted cancer therapy.Education
MD, Johns Hopkins University School of Medicine- Office Phone: 646-888-2138
- Office Phone 646-888-3462
- Office Fax: 646-888-3407
Lab Members
Wassim Abida
Assistant Attending, Laboratory Member
Brett Carver
Associate Attending
Haley Hieronymus
Senior Research Scientist
Phil Iaquinta
Senior Research Scientist
Philip Watson
Assistant Lab Member
Zeda Zhang
GSK Graduate Student
Elizabeth Adams Whicher
Research Fellow
Zhen Cao
NE WGS Graduate Student
Danielle Choi
Senior Animal Husbandry Technician
Tara Guclu
Assistant to Chairman
Jennifer Harris
Fellow
Samuel Haywood
Fellow
Elizabeth Hoover
Senior Research Technician
Wouter Karthaus
Research Assistant
Kayla Lawrence
Senior Research Technician
Eugine Lee
Research Fellow
Young Sun Lee
Research Technician
Ninghui Mao
Senior Research Assistant
Kyrie Pappas
Research Fellow
J. Joshua Smith
Assistant Attending
Chao Wu
Senior Research Scientist
Jimmy Zhao
Fellow
Elizabeth Wasmuth
Research Scholar
Affiliations
Publications
- Wheeler DB, Zoncu R, Root DE, Sabatini DM, Sawyers CL. Identification of an oncogenic RAB protein. Science. 2015 Sep 3. pii: aaa4903. [Epub ahead of print]
- Robinson D, Van Allen EM, Wu YM, Schultz N, Lonigro RJ, Mosquera JM, Montgomery B, Taplin ME, Pritchard CC, Attard G, Beltran H, Abida W, Bradley RK, Vinson J, Cao X, Vats P, Kunju LP, Hussain M, Feng FY, Tomlins SA, Cooney KA, Smith DC, Brennan C, Siddiqui J, Mehra R, Chen Y, Rathkopf DE, Morris MJ, Solomon SB, Durack JC, Reuter VE, Gopalan A, Gao J, Loda M, Lis RT, Bowden M, Balk SP, Gaviola G, Sougnez C, Gupta M, Yu EY, Mostaghel EA, Cheng HH, Mulcahy H, True LD, Plymate SR, Dvinge H, Ferraldeschi R, Flohr P, Miranda S, Zafeiriou Z, Tunariu N, Mateo J, Perez-Lopez R, Demichelis F, Robinson BD, Schiffman M, Nanus DM, Tagawa ST, Sigaras A, Eng KW, Elemento O, Sboner A, Heath EI, Scher HI, Pienta KJ, Kantoff P, de Bono JS, Rubin MA, Nelson PS, Garraway LA, Sawyers CL, Chinnaiyan AM. Integrative clinical genomics of advanced prostate cancer. Cell. 2015 May 21;161(5):1215-28.
Selected Achievements
- Breakthrough Prize in Life Sciences (2013)
- Science of Oncology Award, American Society of Clinical Oncology (2013)
- Stanley J. Korsmeyer Award, American Society of Clinical Investigation (2011)
- Member, National Academy of Sciences (2010)
- Lasker~DeBakey Clinical Medical Research Award, Lasker Foundation (2009)
