Epigenetics Innovation Lab
Senior Research Technician
The Senior Research Technician will perform research activities in collaboration with internal/external personnel to complete science-based projects. He/she will receive detailed instructions while making observations, analyzing data, and interpreting results according to laboratory procedures. The Senior Research Technician will provide support to all technical/research staff and postdocs.
The ideal candidate is:
- Able to work independently within a team-oriented, cooperative environment;
- An effective communicator, capable of determining how best to reach different audiences and executing communications based on that understanding;
- Adept at planning and prioritizing work to meet commitments with a keen eye for detail;
- Action oriented and eager to take on new opportunities and tough challenges with a sense of urgency, high energy, and enthusiasm.
- Perform daily work accurately and help troubleshoot assays to streamline and optimize standard operating procedures, as needed;
- Complete projects including and related to ChIPseq, ATACseq, DNA library preparation, sample quality control;
- Be involved in lab organization;
- Be involved in on-going research projects with peers and research personnel in the laboratory;
- Perform necessary analysis and calculations, records data, and write reports on research findings;
- Purchase equipment and materials for the laboratory;
- Assist Administrative Assistant in generation of purchase order information for supplies and equipment by gathering information for online purchase.
- Bachelor’s in Biology or closely related major with 3+ years related experience or Master’s with at least 1 year of related experience;
- Sound knowledge of molecular biology protocols and equipment;
- To be able to multitask and have strong communication skills;
- Excellent organizational skills.
Computational Epigenetics Lab
Senior Computational Biologist
The core mission of the computational division of the Center for Epigenetics Research is to leverage genomic and epigenomic data to provide novel insights into cancer epigenetics, and to communicate these results to multidisciplinary teams of basic and translational scientists, clinicians, and group leaders. This is accomplished through the integration of gene expression, chromatin structure, and sequence variation with clinical data and experimental animal models, with the goal of understanding, predicting, and gaining therapeutic insight into the epigenetic components of tumorigenesis.
The bioinformatics scientist will be responsible for in depth integrative analysis of multiple genomic and epigenomic data types with a focus on advancing a systems level understanding of cancer epigenetics. He/she will also build analysis frameworks and statistical tools to be utilized more broadly across a range of project goals.
Requirements: PhD or equivalent in bioinformatics, computer science or related field. Ability to maintain detailed records of all analyses and to communicate findings in a clear and concise manner.
- Deep understanding of principles behind current genomic analysis methods;
- Research experience in computational biology, with an emphasis on next-generation sequencing data;
- Extensive experience with scientific computing (R or Matlab);
- Proficient in scripting languages (Perl or Python);
- Familiar with UNIX/Linux environment;
- Knowledge of publicly available bioinformatics tools and software packages;
- Knowledge of C, C++, or Java;
- Solid understanding of probability and statistics;
- Excellent verbal and written communication skills and ability to present analyses to a multi-disciplinary team of clinicians and scientists.