When Is a Headache a Symptom of a Brain Tumor?

Woman wincing in pain

The vast majority of the time, a bad headache is not an indication of a brain tumor. MSK neurologist and supportive care specialist Alan Carver discusses the more common causes of headaches and when to see a doctor if you have a serious one.

A bad headache can be a frightening experience. But sometimes, even scarier than the pounding in your head can be the tricks your mind plays on you as it’s happening.

When that throbbing pain gets unbearable, it’s easy to worry that your headache might be something more serious, like a brain tumor. But Alan Carver, a neurologist and supportive care specialist at Memorial Sloan Kettering, says that the vast majority of the time, a headache is not something to worry about.

“Primary brain tumors are distinctly uncommon,” says Dr. Carver, adding that only five per 100,000 people are diagnosed each year. “The honest truth is that most of the time headaches are not associated with brain tumors, though they can produce severe pain and other unpleasant symptoms.”

Vision problems and other symptoms like nausea, vomiting, and being sensitive to sound and light are much more likely indicators of a migraine headache than a mass in the brain, he says.

MSK neurologist Alan Carver

In fact, only about half of the time will a headache be what brings a person in to see a neurologist, he adds. The symptoms that more commonly suggest a mass in the brain are neurologic: difficulty speaking, weakness on one side of the body, and changes in vision, for example. A seizure is another tip-off, and it can take different forms. Some seizures can include convulsing and a loss of consciousness. Others can be a shorter period of prolonged involuntary movements.

When someone visits a neurologist, a further look at the brain with an MRI is only sometimes necessary. Dr. Carver can usually determine if a person’s headache warrants a closer look by considering a series of questions he abbreviates with the acronym SNOOP.

S: Systemic

“Systemic” refers to what is happening in someone’s body at the time of the headache. A person with a brain tumor likely has other symptoms, and sometimes a preexisting health condition.

“I want to know what else is going on,” Dr. Carver says. “Do they have a fever? Do they have some other illness like cancer or HIV? Is this person sick in some other way? If the person is a young adult and in good health other than the headache, I can often reassure him or her of the extreme unlikelihood of an underlying brain tumor.”

Back to top Arrow (up) icon.Icon pointing upwards. Usually means that the containing element can be opened and closed.

N: Neurologic Exam

A neurologic exam is the gold-standard test given by neurologists and emergency room doctors when someone comes in with a headache. A person with a brain tumor often has a specific neurologic issue that is visible to the naked eye. The person might drag a leg when walking, have trouble speaking, or be unable to raise their arms to equal height. Every time a person has an annual check-up, their doctor is expected to perform a short neurologic exam.

Back to top Arrow (up) icon.Icon pointing upwards. Usually means that the containing element can be opened and closed.

O: Onset

Many headaches that are not dangerous tend to gradually build over hours or even days. A more concerning headache comes on fast and strong, Dr. Carver says.

Back to top Arrow (up) icon.Icon pointing upwards. Usually means that the containing element can be opened and closed.

O: Older

A brain tumor is much more common in older adults than in young people, Dr. Carver says. “If a 22-year-old comes to see me and meets criteria for migraine, and has a normal neurological exam, is there a reason to order an MRI? Absolutely not,” he says.

Back to top Arrow (up) icon.Icon pointing upwards. Usually means that the containing element can be opened and closed.

P: Prior Headache History

When Dr. Carver meets with someone for an appointment, he asks if headaches have been an issue for that person in the past. That can help him determine if the headache is something out of the ordinary or if it is consistent with the person’s medical history.

“People with a prior history of headaches who are unlucky enough later in life to develop a brain tumor are more likely to complain of a headache than people without a history,” Dr. Carver says. “It is therefore especially important to examine people comprehensively to be certain that symptoms or signs aren’t missed.”

Back to top Arrow (up) icon.Icon pointing upwards. Usually means that the containing element can be opened and closed.

Help at MSK

In the very unlikely event that a headache does lead to a brain tumor diagnosis, MSK is one of the top places in the world to come for care. People who have been diagnosed with brain tumors can receive comprehensive care through MSK’s brain tumor service, led by medical oncologist Ingo Mellinghoff. Together with Lisa DeAngelis, Chair of MSK’s Department of Neurology, Dr. Melinghoff and his team are able to offer many more brain tumor treatment options than previously existed and numerous opportunities for people to participate in clinical trials.

And there’s help even if the underlying problem isn’t a tumor. Dr. Carver says that we now know many underlying mechanics of migraines, which has led to successful treatment for most people with this debilitating disorder. He advises anyone with frequent and severe headaches to undergo a comprehensive exam to both assure that nothing is missed and to receive the benefits of successful treatment.

Radiological image of a mouse with glioblastoma.
Brain Tumor Center
Memorial Sloan Kettering’s Brain Tumor Center brings together scientists and clinicians with the goal of developing truly effective brain tumor therapies.
Learn more
Back to top Arrow (up) icon.Icon pointing upwards. Usually means that the containing element can be opened and closed.


My mother was diagnosed with GBM January 19, 2011. The horrible disease stole her life on June 26, 2011 six months, to the day, after her surgery.
She received radiation therapy as well as three rounds of Temodar.
Excellent care at MSKCC by Dr.'s Tabar, Kaley and wonderful nurses.

GBM is a horror. I pray for a cure or new treatment protocol. No loved one, family member, friend or individual should experience this horrific disease.

My husband only 49 was diagnosed in September of 17. Now July 2018 he is going to hospice. He did 30 days tmz with radiation. And one round of maintenance dose of tmz. It’s not effective. I don’t feel radiation is the answer, I believe it was toxic to my husband. The standard of care has to change, brain tumor doctors need to come up with natural treatments as well to help patients in a more well rounded way. It doesn’t work. I’ve been though it and if I ever had it , I would not even bother with SOC. Doctors work hard to change this please!. My two daughters are losing their father and he is a good, smart man and an attorney.

Dear Claudia, we are so very sorry for your loss. Best wishes to you and your family in this difficult time.

Good Day. I would like to send my condolences to the families who have loss their loved ones to, the devil named, brain cancer. My heart really hurts for the family members, of those, who passed on so soon after the diagnosis. My mother was diagnosed with brain cancer in August 2012 and she passed on In July 2016. I thought I was robbed, but now I realized that I was truly grateful to have my mother for the length of time that I had. My mother received chemo, radiation and even participated in a treatment study at MSK. I must say, MSK, is the best. Families, please have faith. Please do all that you can to make this process easy for the children as well.

We are very sorry for your loss. Thank you for your kind words. Best wishes to you.

I lost my father on July 20, 2016 to a short battle with GBM. I wish I could pinpoint when he started exhibiting symptoms. But I didn’t know then what I know now about GBM, which is way more than I have ever cared to know. He had no chance in fighting...the tumor was not methylated. It was a “3 strikes, you’re out” kind of tumor. He had he best of the best at MSKCC. Thank you, Drs. Tabar and Diamond and all of your staff and nurses for doing whatever you could to help my dad. RIP Cosmo Mezzina 7/20/16

Dear Maria, we are very sorry for your loss. Thank you for sharing your story. Best wishes to you and your family.

My 53 year old cousin was just diagnosed with glioblastoma and is being treated by MSK now. Praying that all is being done to save his beautif life and thank you to all the caring doctors and surgeons who devote their lives to saving others

Dear Jodi, we're very sorry to hear about your cousin's diagnosis. We are sending him our best wishes. Thank you for your comment.

My mother was diagnosed with a Glioblastoma at the age of 54 and had the surgery to remove the tumor, however, they told her it would come back and she would probably be gone in 4-6 months. She viewed it more like a challenge than a prognosis....She took radiation, chemo & shark cartilage - relied on her faith in a great God and kept a positive attitude. The brain tumor returned and she did die of a glioblastoma - 19 and a half YEARS later. Not all of those years were easy, but she made the most of them and we're very grateful for the many milestones we had her there for - and I know she was too. She was ready to go at any time, but as long as God and her body allowed - she was going to fight. Do not lose hope - keep fighting - I can say this because I watched and learned from the best!

Dear Jessica, we are sorry for your loss. Thank you for sharing your mother's story.

Is MSKCC doing, or do you know anyone who is doing, genetic research on GBM? My father and both of his parents (married to each other, unrelated) all died of GBM. We have the autopsy slides from my father, he has two siblings still living, and all three of his children have had one or more cancers starting age 25-41, willing to participate in research.

Dear Rebecca, we're very sorry to hear about your family history. If you are interested in learning more about this, you may want to contact our Clinical Genetics Service. They can be reached at 646-888-4050. Thank you for your comment, and best wishes to you.

Add new comment

We welcome your questions and comments. While we share many of them with our world-class doctors and researchers, we regret that in order to protect your privacy, we are not able to make personal medical recommendations on this forum, nor do we publish comments that contain your personal information. If you would like to consult with an MSK doctor, we encourage you to make an appointment at 800-525-2225 or request an appointment online.

Your email address is kept private and will not be shown publicly.