
Emmanouil P. Pappou, MD, PhD, FACS, FASCRS
Colorectal Surgeon
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Areas of Expertise
My Specialties
- Primary and Recurrent Colon, Rectal, Anal, Appendiceal and Small Bowel Cancers
- Carcinoid
- Peritoneal Surface Malignancies
Meet Colorectal Surgeon Emmanouil Pappou
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About Me
- Assistant Attending Surgeon
I am a board-certified colorectal surgeon who specializes in treating gastrointestinal cancers. Specifically, I focus on colon cancer, rectal cancer, appendiceal cancer, and anal cancer.
I have extensive experience doing traditional open surgery and using minimally invasive techniques, such as robotic and laparoscopic surgery. I work closely with my patients, their families, and my colleagues across many disciplines to come up with a treatment plan that best fits my patients’ needs. As a surgeon, I aim to minimize the risks of cancer surgery while having a meaningful, positive impact on my patients’ quality of life.
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I was drawn to the field of surgical oncology and specifically colorectal surgery for several reasons. I admired the dual commitment of a colorectal surgeon to saving lives while at the same time striving to preserve quality of life. I also find it most rewarding to see people get their lives back after they have completed their cancer treatments.
People being treated for colorectal cancer often need to face issues that may be difficult to talk about, such as bowel and sexual function. For this reason, my team and I approach each patient as a member of our family. We treat them with the dignity and respect they deserve. We’ll spend as much time together as needed to ensure that everyone is at ease with our plan moving forward.
Our number-one goal is to cure cancer, but we place equal importance on our patients’ quality of life. That’s why we are developing clinical trials that look at ways to restore or improve function after surgery for colorectal cancer. We’re also developing new tools for early detection and treatment of colorectal and anal cancer.
No two people have the same expectations of surgery. Taking the time to get to know my patients helps me fine-tune the procedure to meet their needs. My team and I are easily accessible and readily available to answer any questions that my patients may have. We are here to guide them and their families before, during, and after surgery.
A colorectal (KOH-loh-REK-tul) surgeon is a doctor with special training in surgery on the colon and rectum.
My Specialties
- Primary and Recurrent Colon, Rectal, Anal, Appendiceal and Small Bowel Cancers
- Carcinoid
- Peritoneal Surface Malignancies
- Minimally Invasive Surgery (Robotic and Laparoscopic)
- Preservation of Bowel, Bladder, and Sexual Function
- Clinical Trials in Surgery
Education
- MD, Technical University of Munich
- PhD, Ludwig-Maximilians-University of Munich
Residencies
- Surgery – Johns Hopkins Hospital
Awards and Honors
- Top Doctors New York Metro Area, Castle Connolly (2023)
- Castle Connolly: America's Top Doctors (2023)
- Johns Hopkins Department of Surgery Core Values in Practice Award (2009)
- Johns Hopkins George D. Zuidema Research Award for Meritorious Laboratory Research (2010)
Fellowships
- Surgical Oncology - The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University
- Colon and Rectal Surgery – NewYork-Presbyterian Hospital/Memorial Sloan Kettering Cancer Center
Board Certifications
- Surgery
- Colon and Rectal Surgery
Insurance Information
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In Network Coverage Type
PPO
In Network Coverage Type
HMO, PPO
In Network Coverage Type
HMO, EPO PPO, POS
In Network Coverage Type
PPO
In Network Coverage Type
EPO
In Network Coverage Type
EPO
In Network Coverage Type
Federal Government
In Network Coverage Type
PPO, POS, EPO, HMO
In Network Coverage Type
State Government
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New Patients
Current Patients
Contact and Location
Dr. Pappou sees patients at three locations.
Looking to see a doctor at a different location? See all MSK locations.
Colleagues
Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.
Clinical Trials

Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.
You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.
Search clinical trialsResearch and Publications
Pappou, E.P. and M.R. Weiser, Robotic colonic resection. J Surg Oncol, 2015
Fu, T., E.P. Pappou, A.A. Guzzetta, M.F. Calmon, L. Sun, A. Herrera, F. Li, C.L. Wolfgang, S.B. Baylin, C.A. Iacobuzio-Donahue, W. Tong, and N. Ahuja, IGFBP-3 Gene Methylation in Primary Tumor Predicts Recurrence of Stage II Colorectal Cancers. Ann Surg, 2015.
Tao Fu, Yanliang Liu, Kai Li, Weiwei Wan, Emmanouil Pappou, Christine Iacobuzio-Donahue, Zachary Kerner, Stephen Baylin, Christopher Wolfgang, and Nita Ahuja.Tumors with unmethylated MLH1 and the CpG island methylator phenotype are associated with a poor prognosis in stage II colorectal cancer patients. Oncotarget 2016.
Visit PubMed for a full listing of Dr. Pappou’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.
See all on PubMedPatient Reviews
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Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Emmanouil P. Pappou discloses the following relationships and financial interests:
No disclosures meeting criteria for time period
If you’re a patient at MSK and would like more information about your doctor’s external relationships, please talk with your doctor.
The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2022 through disclosure submission in spring 2023). This data reflects interests that may or may not still exist. This data is updated annually.
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