Memorial Sloan Kettering surgeon Emmanouil Pappou

Meet Colorectal Surgeon Emmanouil Pappou


Emmanouil P. Pappou, MD, PhD, FACS, FASCRS


Clinical Expertise

Primary and Recurrent Colon, Rectal, Anal, Appendiceal and Small Bowel Cancers; Carcinoid; Peritoneal Surface Malignancies; Minimally Invasive Surgery (Robotic and Laparoscopic); Preservation of Bowel, Bladder, and Sexual Function; Clinical Trials in Surgery

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Accepted Insurance Providers

Dr. Pappou accepts the following list of insurance providers. Select your insurance provider to see more details.

Contact and Location

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Find a Convenient Location

Memorial Sloan Kettering has locations throughout New York City, Long Island, New Jersey, and Westchester. These locations offers many services, including screening, chemotherapy, and medical testing.

About Me


MD, Technical University of Munich; PhD, Ludwig-Maximilians-University of Munich


Surgery – Johns Hopkins Hospital


Surgical Oncology - The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University; Colon and Rectal Surgery – NewYork-Presbyterian Hospital/Memorial Sloan Kettering Cancer Center

Board Certifications

Surgery; Colon and Rectal Surgery

I am a board-certified colorectal surgeon who specializes in treating gastrointestinal cancers. Specifically, I focus on colon cancer, rectal cancer, appendiceal cancer, and anal cancer. I have extensive experience doing traditional open surgery and using minimally invasive techniques, such as robotic and laparoscopic surgery. I work closely with my patients, their families, and my colleagues across many disciplines to come up with a treatment plan that best fits my patients’ needs. As a surgeon, I aim to minimize the risks of cancer surgery while having a meaningful, positive impact on my patients’ quality of life.

I was drawn to the field of surgical oncology and specifically colorectal surgery for several reasons. I admired the dual commitment of a colorectal surgeon to saving lives while at the same time striving to preserve quality of life. I also find it most rewarding to see people get their lives back after they have completed their cancer treatments.

People being treated for colorectal cancer often need to face issues that may be difficult to talk about, such as bowel and sexual function. For this reason, my team and I approach each patient as a member of our family. We treat them with the dignity and respect they deserve. We’ll spend as much time together as needed to ensure that everyone is at ease with our plan moving forward.

Our number-one goal is to cure cancer, but we place equal importance on our patients’ quality of life. That’s why we are developing clinical trials that look at ways to restore or improve function after surgery for colorectal cancer. We’re also developing new tools for early detection and treatment of colorectal and anal cancer.

No two people have the same expectations of surgery. Taking the time to get to know my patients helps me fine-tune the procedure to meet their needs. My team and I are easily accessible and readily available to answer any questions that my patients may have. We are here to guide them and their families before, during, and after surgery.

I work closely with my patients, their families, and my colleagues across many disciplines to come up with a treatment plan that best fits my patients’ needs.

Dr. Pappou

Awards and Honors

  • Johns Hopkins Department of Surgery Core Values in Practice Award (2009)
  • Johns Hopkins George D. Zuidema Research Award for Meritorious Laboratory Research (2010)


Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.

Clinical Trials

Smiling doctors in the lab

Find a Clinical Trial for You

Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.

You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.

Research and Publications

Pappou, E.P. and M.R. Weiser, Robotic colonic resection. J Surg Oncol, 2015

Fu, T., E.P. Pappou, A.A. Guzzetta, M.F. Calmon, L. Sun, A. Herrera, F. Li, C.L. Wolfgang, S.B. Baylin, C.A. Iacobuzio-Donahue, W. Tong, and N. Ahuja, IGFBP-3 Gene Methylation in Primary Tumor Predicts Recurrence of Stage II Colorectal Cancers. Ann Surg, 2015.

Tao Fu, Yanliang Liu, Kai Li, Weiwei Wan, Emmanouil Pappou, Christine Iacobuzio-Donahue, Zachary Kerner, Stephen Baylin, Christopher Wolfgang, and Nita Ahuja.Tumors with unmethylated MLH1 and the CpG island methylator phenotype are associated with a poor prognosis in stage II colorectal cancer patients. Oncotarget 2016.

Publications on PubMed

Visit PubMed for a full listing of Dr. Pappou’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.