Louise Catherine Connell, MB BCh BAO, BMedSc

Memorial Sloan Kettering medical oncologist Louise Connell
LocationA pin, used as a metaphor for the concept of location. Locations Plus and Minus IconIcon showing a plus/minus toggle, indicating that the surrounding element can be opened and closed.
Phone iconAn icon showing a telephone. New Patient Appointments Plus and Minus IconIcon showing a plus/minus toggle, indicating that the surrounding element can be opened and closed.

About Me

I am a medical oncologist whose practice is dedicated to caring for people with gastrointestinal cancers. These include colon cancer, rectal cancer, and appendiceal cancer. I also have expertise in treating hepatobiliary cancers. I specialize in systemic chemotherapy, where the treatment circulates throughout the body, and regional chemotherapy, meaning the drug is delivered directly to the liver or abdomen. I see patients at MSK’s Rockefeller Outpatient Pavilion, in Manhattan.

The goal of my research is to develop new, more-personalized therapies for people with colorectal and hepatobiliary cancers. For example, we are working to develop immunotherapy and molecular-based approaches to effectively treat these diseases. I have a particular interest in advancing our understanding of colorectal cancers at the molecular level so that we can learn how and why they grow and spread.

As a medical student unsure of the exact path my career would take, my family was impacted by cancer. The journey that followed influenced me both in terms of my career choices and goals, and also how I care for patients today. My experience being on the other side of the consultation desk helped me to understand and appreciate what patients and their families go through after receiving a cancer diagnosis.

When caring for my patients, I aim to provide the best evidence-based treatments and to surround them with compassion. I place a great deal of emphasis on communication to help reduce their distress and maximize their quality of life.

  • Clinical Expertise: Colon Cancer; Rectal Cancer; Hepatic Arterial Infusion Chemotherapy for Colorectal Cancer
  • Awards and Honors: Irish Society of Medical Oncology Scholarship Award (2013); Ainsworth Scholarship (2014); American Society of Clinical Oncology (ASCO) Young Investigator Award (2016)
  • Languages Spoken: English; Portuguese
  • Education: MB BCh BAO BMedSc, University College Cork, Ireland
  • Residencies: Internal Medicine - Royal College of Physicians of Ireland
  • Fellowships: Medical Oncology - Royal College of Physicians of Ireland; Advanced Medical Oncology - Memorial Sloan Kettering Cancer Center
  • Board Certifications: Internal Medicine (Ireland); Medical Oncology (Ireland and Europe)


Relevance of CEA and LDH in relation to KRAS status in patients with unresectable colorectal liver metastases. Connell LC, Boucher TM, Chou JF, Capanu M, Maldonado S, Kemeny NE.J Surg Oncol. 2017 Mar;115(4):480-487. doi: 10.1002/jso.24536. Epub 2016 Dec 23.PMID:28008623

Response rates of hepatic arterial infusion pump therapy in patients with metastatic colorectal cancer liver metastases refractory to all standard chemotherapies. Cercek A, Boucher TM, Gluskin JS, Aguiló A, Chou JF, Connell LC, Capanu M, Reidy-Lagunes D, D’Angelica M, Kemeny NE.J Surg Oncol. 2016 Nov;114(6):655-663. doi: 10.1002/jso.24399. Epub 2016 Aug 26.PMID:27566258

The Rising Incidence of Younger Patients With Colorectal Cancer: Questions About Screening, Biology, and Treatment. Connell LC, Mota JM, Braghiroli MI, Hoff PM. Curr Treat Options Oncol. 2017 Apr;18(4):23. doi: 10.1007/s11864-017-0463-3. PMID:28391421

Combined Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma. Connell LC, Harding JJ, Shia J, Abou-Alfa GK.Chin Clin Oncol. 2016 Oct;5(5):66. doi: 10.21037/cco.2016.10.02. PMID: 27829279 

Advanced Hepatocellular Cancer: The Current State of Future Research. Connell LC, Harding JJ,Abou-Alfa GK. Curr Treat Options Oncol. 2016 Aug;17(8):43. doi: 10.1007/s11864-016-0415-3. PMID:27344158

Toxicities of the anti-PD-1 and anti-PD-L1 immune checkpoint antibodies.  Naidoo J, Page DB, Li BT, Connell LC, Schindler K, Lacouture ME, Postow MA, Wolchok JD.  Ann Oncol. 2015 Dec;26(12):2375-91. PMID:27072927

Visit PubMed for a full listing of Louise Catherine Connell’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Clinical Trials

As home to one of the world’s top cancer research centers, Memorial Sloan Kettering is typically involved in more than 900 clinical trials at a given time. Currently, clinical trials focused on the conditions I treat are enrolling new patients. If you’re interested in joining a clinical trial, click to learn about the trial’s purpose, eligibility criteria, and how to get more information.

Learn more Arrow rightAn icon showing an arrow pointing to the right.


Most major health insurers offer plans that include MSK as one of their in-network providers. If MSK is in-network, it means all our doctors are too. Medicare and New York State Medicaid also provide benefits for care at MSK.

Learn more Arrow rightAn icon showing an arrow pointing to the right.