Michael F. Berger, PhD

Michael F. Berger, PhD

Geneticist

Titles

Associate Director, Marie-Josée and Henry R. Kravis Center for Molecular Oncology

Clinical Expertise

Genomics and Computational Biology

New Patient Appointments

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Accepted Insurance Providers

Dr. Berger accepts the following list of insurance providers. Select your insurance provider to see more details.

Aetna

Memorial Sloan Kettering is an in-network provider with Aetna HMO, POS, and PPO plans. Aetna does not include us in any of the plans you can purchase through the insurance exchanges or through Medicare. Please ask your insurance if you need a one-time referral.

Blue Cross Blue Shield

In New York State

Memorial Sloan Kettering is an in-network provider with Empire Blue Cross Blue Shield (Wellpoint) of New York HMO, EPO, PPO, and POS plans, with the following exceptions:

  • Empire Blue Cross Blue Shield does not include us in any of the plans you can buy through the insurance exchanges.
  • Memorial Sloan Kettering is not an in-network provider for Empire's Medicare Managed Care plan known as Mediblue).
  • The Empire Indemnity Plan provides limited coverage for our services.

Memorial Sloan Kettering is a designated Center of Excellence by Blue Cross Blue Shield.

In New Jersey

Memorial Sloan Kettering is an in-network provider with some Horizon Blue Cross Blue Shield of New Jersey plans for individuals, families, and small businesses. For example, the PPO plan is in-network with our Manhattan locations.

Horizon Blue Cross HMO is only in-network with our Basking Ridge, Bergen and Monmouth locations. It does not allow access to our Manhattan facilities.

Horizon Blue Cross PPO is in network with our Basking Ridge, Bergen, Monmouth and Manhattan locations.

OMNIA Plans: Tier I EPO based plan policy is only in-network with our Basking Ridge, Bergen and Monmouth locations and does not allow access to our Manhattan sites. Tier II EPO is only in-network with our Manhattan sites if it is a blue-card plan (there would be a suitcase logo indicating PPO on the front of the card).

Other plans may only be in-network at our Basking Ridge, Bergen or Monmouth locations.

Outside New York State and New Jersey

Some, but not all, Blue Cross Blue Shield plans outside of New York and New Jersey include Memorial Sloan Kettering as an in-network provider. Contact your insurance to find out if your plan provides in-network access to Memorial Sloan Kettering.

CIGNA

Memorial Sloan Kettering is an in-network provider with CIGNA's HMO, POS, and PPO plans. CIGNA does not include us in any of the plans you can buy through the insurance exchanges.

  • If you are a New York State resident: Please ask your insurance if you need a one-time referral.
  • If you live outside of New York State: Please ask your insurance if you have in-network access to Memorial Sloan Kettering.

Memorial Sloan Kettering is a designated Center of Excellence by Blue Cross Blue Shield.

EmblemHealth (including GHI, HIP, ConnectiCare, and Vytra)

Memorial Sloan Kettering is an in-network provider with EmblemHealth’s PPO, EPO, POS, and HMO plans as well as their Enhanced Care Prime Network, which supports Medicaid Managed Care and Child Health Plus and Medicare plans. Memorial Sloan Kettering is also in-network with the New York State Essential Emblem Health plan, which can be purchased on the insurance exchange. Emblem Health does not include us in any of its Medicare plans or in any of its Select Care network plans. You must bring a referral from your Emblem primary care doctor to your first appointment.

Empire Blue Cross Blue Shield Health Plus

Formerly known as Health Plus Amerigroup, Empire Blue Cross Blue Shield Health Plus is an in-network provider with Memorial Sloan Kettering. You will need a one-time referral from your primary care doctor.

Health Insurance Exchanges

We understand that there may be many complexities involved with insurance coverage purchased through the health exchange network of the Affordable Care Act. We're here to help. If you have questions about how your care will be covered by an insurance provider, or need help navigating a change in coverage, please call us at 646-227-3378; if you are not a resident of New York, you can call us at 866-248-1274. Our team is here to listen to your concerns and assist you in any way we can. We want our care to be as accessible and affordable for as many people as possible.

HealthSmart

Memorial Sloan Kettering is an in-network provider with HealthSmart’s Accel, HSPC, and HPO networks.

Humana

Memorial Sloan Kettering is a designated Center of Excellence by Humana.

Interlink Health Services

Memorial Sloan Kettering is a designated Center of Excellence by Interlink Health Services.

Lifetrac

Memorial Sloan Kettering is a designated Center of Excellence by Lifetrac.

MagnaCare

Memorial Sloan Kettering is an in-network provider for all MagnaCare health plans except those products you can buy through the insurance exchanges.

Medicaid

New York State Medicaid covers physician and hospital services at Memorial Sloan Kettering. Patients are responsible for co-payments.

We also have contractual relationships involving Medicaid Managed Care plans. MSK is an in-network provider with Medicaid NY Emblem Health (formerly known as HIP) and Medicaid NY Empire Blue Cross Blue Shield HealthPlus (formerly known as Amerigroup). You will need a one-time referral from your primary care doctor.

Medicare

Hospital and physician services at Memorial Sloan Kettering are covered by standard Medicare insurance. You are responsible for co-insurance and deductible costs. 

In New York: Memorial Sloan Kettering’s New York locations are in-network with the Emblem Medicare Advantage Plans.

In New Jersey: Memorial Sloan Kettering’s  New Jersey locations in Basking Ridge, Bergen and Monmouth are in-network with the Horizon Medicare Advantage Plan. This plan is not accepted for care provided at MSK’s New York locations.

If you are enrolled in any other Medicare Advantage plan, please contact your insurance carrier to determine your benefits and coverage at Memorial Sloan Kettering since your access may be limited.

Multiplan/Beech Street/PHCS

Memorial Sloan Kettering is an in-network provider with some Multiplan/Beech Street/PHCS plans. Contact your insurance carrier to find out if your plan provides in-network access to Memorial Sloan Kettering.

Memorial Sloan Kettering is a designated Center of Excellence by Multiplan.

Multiple Insurance Plans

If you are covered by more than one insurance plan, you will want to determine your benefits from both plans. First, you need to determine which one is your primary insurance provider by contacting your employee benefits office or your insurance carriers. After you find out which is your primary insurance provider, you should then contact your insurance carrier to determine if you have access to Memorial Sloan Kettering.

MVP

Memorial Sloan Kettering is an in-network provider with some MVP plans. Contact your insurance carrier to find out if your plan provides in-network access to Memorial Sloan Kettering.

New York State Employee Health Insurance Plan (Empire Plan)

Memorial Sloan Kettering is an in-network provider for New York State employees who have enrolled in UnitedHealthcare's Cancer Resource Services. If you have the Empire Plan, you should call Cancer Resources Services at 866-936-6002 to verify and enroll in this coverage.

Oscar

Memorial Sloan Kettering is in-network with Oscar's Circle Plus Network, a part of its Small Group Broad line that is offered only to select small business groups. Oscar does not include Memorial Sloan Kettering as an in-network provider for any of its individual plans. Please confirm eligibility with your insurance carrier.

Other Coverage Options

We have agreements with several insurance companies that may provide additional coverage for cancer patients. These benefit programs include:

  • AXA Assistance USA
  • Beech Street
  • Integrated Health Plans
  • National Health Administrators
  • National Preferred Provider Network
  • UnitedHealthcare's Cancer Resource Services
  • United Resource Network
  • Veterans Choice Program
Oxford

Memorial Sloan Kettering is an in-network provider with Oxford’s Freedom and Liberty plans as well as the Metro Plan (which is only offered to small business groups and no longer offered as individual plans). Please confirm with your insurance if you need a one-time referral. Note: Oxford's Medicare Managed Care plan — Secure Horizon — does not include Memorial Sloan Kettering as an in-network provider. Oxford does not include us in any of the plans you can buy through the insurance exchanges.

QualCare

Memorial Sloan Kettering is an in-network provider with QualCare's PPO and HMO/POS network.

Specialty Care Management

Memorial Sloan Kettering is a designated Center of Excellence by Specialty Care Management.

TRICARE

Hospital and physician services at Memorial Sloan Kettering are covered by TRICARE. You are responsible for co-insurance and deductible costs.

UnitedHealthcare

Memorial Sloan Kettering is an in-network provider with UnitedHealthCare's HMO, POS, and PPO plans. Please confirm with your insurance if a one-time referral is needed.

UnitedHealthCare's Medicare Managed Care plan does not include Memorial Sloan Kettering as an in-network provider.

United does not include us in any of the plans you can buy through the insurance exchanges.

Memorial Sloan Kettering is a designated Center of Excellence by UnitedHealthcare.

World Trade Center Health Program

Memorial Sloan Kettering is an in-network provider with the World Trade Center Health Program.

Contact and Location

Find a Convenient Location

Memorial Sloan Kettering has locations throughout New York City, Long Island, New Jersey, and Westchester. These locations offers many services, including screening, chemotherapy, and medical testing.

See all locations

About Me

Education

PhD, Harvard University

Fellowships

The Broad Institute of MIT and Harvard

I am Associate Director of the Marie-Josée and Henry R. Kravis Center for Molecular Oncology and an assistant attending geneticist in the Department of Pathology. I have expertise in cancer genetics, computational biology, and high-throughput DNA sequencing technology. My research is focused on developing and applying methods of profiling tumor DNA in order to characterize the genetic makeup of individual cancers. Knowledge of patient-specific genetic mutations can be used to predict outcomes and inform treatment options, ultimately enabling more personalized cancer medicine.

With recent innovations in DNA sequencing technology, one can cheaply and quickly capture the relevant genomic information in an individual patient’s tumor. In collaboration with oncologists, pathologists, and other translational researchers, I am leveraging the extensive institutional collection of annotated tumor specimens spanning all cancer subtypes to identify novel, clinically useful biomarkers that may correlate with outcomes or predict responses to novel therapeutic agents. As a member of the Molecular Diagnostics Service, I helped lead the development of a robust molecular profiling platform and accompanying analysis pipeline for use in clinical trials and real-time patient management. Altogether, these activities aim to improve clinical practice by empowering oncologists to make treatment decisions informed by the molecular composition of their patients’ tumors.

Colleagues

Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.

Clinical Trials

Find a Clinical Trial for You

Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.

You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.

Search clinical trials

Research and Publications

View Dr. Berger's Lab

Recurrent SMARCA4 mutations in small cell carcinoma of the ovary.  Jelinic P, Mueller JJ, Olvera N, Dao F, Scott SN, Shah R, Gao J, Schultz N, Gonen M, Soslow RA, Berger MF, Levine DA. Nat Genet. 2014 May;46(5):424-6. doi: 10.1038/ng.2922. Epub 2014 Mar 23.

 Tumor genetic analyses of patients with metastatic renal cell carcinoma and extended benefit from mTOR inhibitor therapy.  Voss MH, Hakimi AA, Pham CG, Brannon AR, Chen YB, Cunha LF, Akin O, Liu H, Takeda S, Scott SN, Socci ND, Viale A, Schultz N, Sander C, Reuter VE, Russo P, Cheng EH, Motzer RJ, Berger MF, Hsieh JJ. Clin Cancer Res. 2014 Apr 1;20(7):1955-64. do: 10.1158/1078-0432.CCR-13-2345. Epub 2014 Mar 12.

ESR1 ligand-binding domain mutations in hormone-resistant breast cancer. Toy W, Shen Y, Won H, Green B, Sakr RA, Will M, Li Z, Gala K, Fanning S, King TA, Hudis C, Chen D, Taran T, Hortobagyi G, Greene G, Berger M, Baselga J, Chandarlapaty S. Nat Genet. 2013 Dec;45(12):1439-45. doi: 10.1038/ng.2822. Epub 2013 Nov 3.

Detecting somatic genetic alterations in tumor specimens by exon capture and massively parallel sequencing. Won HH, Scott SN, Brannon AR, Shah RH, Berger MF. J Vis Exp. 2013 Oct 18;(80):e50710. doi: 10.3791/50710.

Genome sequencing identifies a basis for everolimus sensitivity. Iyer G, Hanrahan AJ, Milowsky MI, Al-Ahmadie H, Scott SN, Janakiraman M, Pirun M, Sander C, Socci ND, Ostrovnaya I, Viale A, Heguy A, Peng L, Chan TA, Bochner B, Bajorin DF, Berger MF, Taylor BS, Solit DB. Science. 2012 Oct 12;338(6104):221. doi: 10.1126/science.1226344. Epub 2012 Aug 23.

Melanoma genome sequencing reveals frequent PREX2 mutations. Berger MF, Hodis E, Heffernan TP, Deribe YL, Lawrence MS, Protopopov A, Ivanova E, Watson IR, Nickerson E, Ghosh P, Zhang H, Zeid R, Ren X, Cibulskis K, Sivachenko AY, Wagle N, Sucker A, Sougnez C, Onofrio R, Ambrogio L, Auclair D, Fennell T, Carter SL, Drier Y, Stojanov P, Singer MA, Voet D, Jing R, Saksena G, Barretina J, Ramos AH, Pugh TJ, Stransky N, Parkin M, Winckler W, Mahan S, Ardlie K, Baldwin J, Wargo J, Schadendorf D, Meyerson M, Gabriel SB, Golub TR, Wagner SN, Lander ES, Getz G, Chin L, Garraway LA. Nature. 2012 May 9;485(7399):502-6. doi: 10.1038/nature11071.

High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing. Wagle N1, Berger MF, Davis MJ, Blumenstiel B, Defelice M, Pochanard P, Ducar M, Van Hummelen P, Macconaill LE, Hahn WC, Meyerson M, Gabriel SB, Garraway LA.  Cancer Discov. 2012 Jan;2(1):82-93. doi: 10.1158/2159-8290.CD-11-0184. Epub 2011 Nov 7.

Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling. Wagle N, Emery C, Berger MF, Davis MJ, Sawyer A, Pochanard P, Kehoe SM, Johannessen C, MacConaill LE, Hahn WC, Meyerson M, Garraway LA. J Clin Oncol. 2011 Mar 7. (Epub ahead of print).

The genomic complexity of primary human prostate cancer. Berger MF, Lawrence MS, Demichelis F, Drier Y, Cibulskis K, Sivachenko AY, Sboner A, Esgueva R, Pflueger D, SougnezC, Onofrio R, Carter SL, Park K, Habegger L, Ambrogio L, Fennell T, Parkin M, Saksena G, Voet D, Ramos AH, Pugh TJ, Wilkinson J, Fisher S, Winckler W, Mahan S, Ardlie K, Baldwin J, Simons JW, Kitabayashi N, MacDonald TY, Kantoff PW, Chin L, Gabriel SB, Gerstein MB, Golub TR, Meyerson M, Tewari A, Lander ES, Getz G, Rubin MA, Garraway LA. Nature. 2011 Feb 10;470(7333):214-20.

Integrative analysis of the melanoma transcriptome. Berger MF, Levin JZ, Vijayendran K, Sivachenko A, Adiconis X, Maguire J, Johnson LA, Robinson J, Verhaak RG, Sougnez C, Onofrio RC, Ziaugra L, Cibulskis K, Laine E, Barretina J, Winckler W, Fisher DE, Getz G, Meyerson M, Jaffe DB, Gabriel SB, Lander ES, Dummer R, Gnirke A, Nusbaum C, Garraway LA. Genome Research. 2010 Apr;20(4):413-27. Epub 2010 Feb 23.

Diversity and complexity in DNA recognition by transcription factors. Badis G, Berger MF, Philippakis AA, Talukder S, Gehrke AR, Jaeger SA, Chan ET, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang CF, Coburn D, Newburger DE, Morris Q, Hughes TR, Bulyk ML. Science. 2009 Jun 26;324(5935):1720-3. Epub 2009 May 14.

Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Berger MF, Badis G, Gehrke AR, Talukder S, Philippakis AA, Peña-Castillo L, Alleyne TM, Mnaimneh S, Botvinnik OB, Chan ET, Khalid F, Zhang W, Newburger D, Jaeger SA, Morris QD, Bulyk ML, Hughes TR. Cell. 2008 Jun 27;133(7):1266-76.

Compact, universal DNA microarrays to comprehensively determine transcription-factor binding site specificities. Berger MF, Philippakis AA, Qureshi AM, He FS, Estep PW 3rd, Bulyk ML. Nature Biotechnology. 2006 Nov;24(11):1429-35. Epub 2006 Sep 24.

 

Publications on PubMed

Visit PubMed for a full listing of Dr. Berger’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.

See all on PubMed