Simon N. Powell, MD, PhD, FRCP -- Chair, Department of Radiation Oncology; Enid A. Haupt Chair in Radiation Oncology

Simon N. Powell, MD, PhD, FRCP

Radiation Oncologist

Titles

Chair, Department of Radiation Oncology; Enid A. Haupt Chair in Radiation Oncology

Clinical Expertise

Radiation Oncology; Breast Cancer

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Accepted Insurance Providers

Dr. Powell accepts the following list of insurance providers. Select your insurance provider to see more details.

Contact and Location

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Memorial Sloan Kettering has locations throughout New York City, Long Island, New Jersey, and Westchester. These locations offers many services, including screening, chemotherapy, and medical testing.

About Me

Education

MBBS, University of London

Residencies

Medicine - University of London Teaching Hospitals

Fellowships

Clinical Oncology - Royal Marsden Hospital; Radiation Oncology - Harvard Medical School

Board Certifications

Radiation Oncology; Internal Medicine (UK)

I am a radiation oncologist who cares for people with breast cancer. I am Chair of the Department of Radiation Oncology and have been practicing medicine for 35 years. I see approximately 200 new breast cancer patients each year at Memorial Sloan Kettering in Manhattan.

When patients come to see me, they are worried about whether we can get rid of their cancer. Many patients read about their diagnosis on the internet, and the information they find can be very scary. I always make it a priority to answer all of my patients’ questions so that they feel reassured. I want them to know that they are getting the best care possible.

My research is focused on breast cancer. I have received funding from the National Institutes of Health since 1992 and am an expert in understanding how DNA repair genes like BRCA1 and BRCA2 work to fix DNA damage, as well as how a person’s genetics may influence his or her response to radiation therapy.   

 At MSK, we are leading the way in the use of advanced radiation techniques to ensure our patients have the best outcomes possible. For our early-stage breast cancer patients, we are using hypofractionated whole-breast irradiation. This means patients are receiving fewer total treatment sessions in a shorter time period, with a slightly higher dose given each treatment day. We also have a robust delivery system for partial breast irradiation. We now deliver treatment once per day, which helps our patients tolerate their treatment better.

I have experience treating people with recurrent or metastatic triple-negative breast cancer using radiation in combination with chemotherapy, targeted therapies, and immunotherapies.

For some people, breast cancer treatment can negatively affect the heart. At MSK, we have a program dedicated to assessing this problem. We are leaders in the field of deep inspiration breath-hold techniques, which can help lessen the cardiac side effects for our breast cancer patients. We are also using proton therapy to target tumors more precisely, which can reduce the risk of other treatment-related side effects.

I am a member of advisory boards for several cancer centers in the US and abroad, including the Netherlands Cancer Institute, Winship Cancer Institute of Emory University, University of Michigan Cancer Center, and the University of Florida Health Cancer Center.

In my free time, I enjoy theater, opera, ballet, country-specific versions of history, football, American football, and golf.

I always make it a priority to answer all of my patients’ questions so that they feel reassured. I want them to know that they are getting the best care possible.

Dr. Powell

Awards and Honors

  • Castle Connolly: New York Magazine Top Doctors (2016-2018)
  • America’s Top Doctors
  • Top Doctors New York Metro Area
  • Boston Top Doctors
  • St. Louis Top Doctors

Colleagues

Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.

Clinical Trials

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Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.

You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.

Research and Publications

My research is focused on breast cancer. I have received funding from the National Institutes of Health since 1992 and am an expert in understanding how DNA repair genes like BRCA1 and BRCA2 work to fix DNA damage, as well as how a person’s genetics may influence his or her response to radiation therapy.

View Dr. Powell's Lab

Publications on PubMed

Visit PubMed for a full listing of Dr. Powell’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.