Hereditary Prostate Cancer


Learn more about Memorial Sloan Kettering’s guidelines for prostate cancer screening.

Prostate cancer is one of the most common cancer types among men. Most prostate cancers are not associated with a hereditary predisposition, but prostate cancers that have spread or are more aggressive are more likely to be associated with a hereditary predisposition. The aggressiveness of prostate cancer is determined by what is called the Gleason score.  Those with score of 7 or higher are considered more aggressive.

Mutations in the following genes can be passed down from a parent to a child and increase a man’s chance of developing prostate cancer:

Other genes that may be associated with an increased risk for prostate cancer are currently under investigation.