Other Plasma-Cell Diseases

Memorial Sloan Kettering doctors are experienced in caring for patients with other plasma cell diseases related to multiple myeloma. These include systemic amyloidoses — a group of rare and sometimes serious disorders — as well as less severe conditions such as solitary plasmacytoma and monoclonal gammopathy of undetermined significance (MGUS).

Learn more about these multiple myeloma-related blood diseases.

  • Systemic Amyloidoses

    In this group of related diseases, a substance called amyloid builds up in tissues throughout the body, interfering with organ function and eventually causing affected organs to fail.

  • Solitary Plasmacytoma

    In solitary plasmacytoma, which is similar to multiple myeloma, the disease is restricted to a single area of the body — usually a bone, but sometimes an organ.

  • Monoclonal Gammopathy of Undetermined Significance

    MGUS, a condition that leads to moderately elevated levels of immunoglobulin protein in the blood, has no symptoms but is precancerous, and in rare instances may progress to multiple myeloma.