Soft Tissue Sarcoma Clinical Trials and Research

Sarcoma expert Ping Chi meets with research technician Makhzuna Khudoynazarova
Physician-scientist Ping Chi develops clinical trials to personalize treatment for people with sarcoma.

Memorial Sloan Kettering doctors are constantly working to improve treatment for people with soft tissue sarcoma through clinical trials. Participating in a clinical trial may give you access to treatments that are not widely available elsewhere. These studies may offer additional options if the cancer has returned after standard treatment.

Our experts can help determine which clinical trial is right for you. Browse our listing of clinical trials that are currently enrolling new patients.

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5 Clinical Trials found
A Phase 2 Study of Pembrolizumab Immunotherapy for People With Ultra-Rare Sarcomas
Pembrolizumab takes the brakes off the immune system so immune cells can find and hopefully attack cancer cells. It is given intravenously (by vein).
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau
A Phase I/II Study of INCMGA00012 Immunotherapy with Gemcitabine and Docetaxel in People with Advanced Soft Tissue Sarcoma
The purpose of this study is to assess the safety and effectiveness of giving the investigational immunotherapy drug INCMGA00012 in combination with gemcitabine and docetaxel in patients with inoperable or metastatic soft tissue sarcoma. Gemcitabine and docetaxel are standard treatments for this disease; researchers believe that adding INCMGA00012 may make treatment more effective.
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau
A Phase 1 Study of MQ710 in People With Solid Tumors
In this study, researchers are finding the highest dose of MQ710 to use safely in people with certain types of advanced cancer. The people in this study have solid tumors that came back or grew even after treatment. In a later part of the study, the researchers will assess MQ710 plus another drug called pembrolizumab.
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau
A Phase 3 Study of Doxorubicin Alone or With Pembrolizumab to Advanced Sarcomas
Researchers are comparing treatment with doxorubicin chemotherapy and pembrolizumab immunotherapy to doxorubicin alone for advanced sarcoma. The people in this study have undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma. Their cancers have metastasized (spread) or are inoperable (cannot be taken out with surgery).
New York City, Basking Ridge, Bergen, Nassau
A Phase II Study of Pembrolizumab Immunotherapy plus Local Chemotherapy using Isolated Limb Infusion for Patients with Advanced Sarcoma in the Arm or Leg
Isolated limb infusion (ILI) is a way to give anticancer drugs directly into an arm or leg to treat a sarcoma. However, despite this treatment, sometimes the cancer still spreads to other parts of the body. In this study, researchers want to see if adding the immunotherapy drug pembrolizumab to ILI treatment with the chemotherapy drugs melphalan and dactinomycin can help prevent the spread of cancer and increase the effectiveness of the ILI treatment in people with advanced sarcoma.
New York City, Commack, Basking Ridge, Westchester, Monmouth, Bergen, Nassau