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Alban Ordureau explores molecular signaling pathways that regulate cellular homeostasis, with a focus on the ubiquitin and autophagy systems.
The Minn Lab investigates how cancers evolve under chronic inflammation and persistent immune pressure to acquire resistance to immunotherapies, with the goal of developing innovative therapies to restore anti-tumor immunity.
Joan Massagué studies the control of stem cell growth and phenotype in tumor progression, metastasis, and response to therapy.
Physician-scientist Viviane Tabar focuses on stem cells as tools for brain repair and for modeling brain cancer.
The Kushal Dey lab focuses on developing machine learning models and computational pipelines that integrate genomic and epigenomic data.
Physician-scientist Charles Rudin focuses on the development and testing of novel therapeutic approaches to lung cancer in preclinical models.
The Łuksza Lab develops predictive models of immune-driven evolution to understand how tumors and viruses adapt under immune pressure.
The Hite laboratory studies the mechanisms of ion and metabolite transport and the maintenance of genomic integrity.
Optical engineer Milind Rajadhyaksha studies confocal microscopy for the imaging of cancer, technology development, and translational and clinical studies in skin and head and neck cancers.