Colin Begg, PhD

Chairman, Attending Biostatistician

Colin Begg, PhD

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University of Glasgow, UK

Current Research Interests

Dr. Begg has long-standing interests in cancer epidemiology, health services research, clinical trials, genetics and genomics, and the statistical methods that support scientific studies in these disciplines. He has collaborated closely with countless departmental colleagues over the years, most recently with Marinela Capanu, Angela Green, Audrey Mauguen, Irene Orlow, Irina Ostrovnaya, Venkatraman Seshan, Ronglai Shen, Allison Lipitz-Snyderman, Axel Martin and post-doctoral fellows Saptarshi Chakraborty and Zoe Guan. He serves as a scientific advisor to numerous other cancer centers and extra-mural research groups. He is a joint principal investigator of the NCI-funded international GEM study that addresses the genetic and environmental risks of melanoma and of an NCI R25 training grant. Dr. Begg also currently serves as Editor-in-Chief of the international scholarly journal Clinical Trials, the journal of the Society for Clinical Trials.


Selected peer-reviewed publications:

  1. Begg, CB. A strategy for distinguishing optimal cancer subtypes. International Journal of Cancer 2011;129:931-937. PMCID: PMC3043163
  2. Ostrovnaya I, Seshan VE, Begg CB. Using somatic mutation data to test tumors for clonal relatedness. Annals of Applied Statistics 2015;9:1533-1548. PMCID: PMC4649945
  3. Begg CB, Ostrovnaya I, Carniello JV, Sakr RA, Giri D, Towers R, Schizas M, De Brot M, Andrade VP, Mauguen A, Seshan VE, King TA. Clonal relationships between lobular carcinoma in situ and other breast malignancies. Breast Cancer Research 2016;18:66. PMCID: PMC4918003
  4. Mauguen A, Zabor EC, Thomas NE, Berwick M, Seshan VE, Begg CB. Defining cancer subtypes with distinctive etiologic profiles: an application to the epidemiology of melanoma. Journal of the American Statistical Association 2017;112: 54-63. PMCID: PMC5460661
  5. Begg CB, Rice MS, Zabor EC, Tworoger SS. Examining the common aetiology of serous ovarian cancers and basal-like breast cancers using double primaries. British Journal of Cancer 2017;116:1088-1091. PMCID: PMC5396122

Visit PubMed for a full listing of Colin Begg’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.


Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Colin Begg discloses the following relationships and financial interests:

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