The Epidemiology Service focuses on cancer prevention by investigating the etiology of cancer and by evaluating the effect of screening. Primary prevention investigations have focused on the study of genetic susceptibility to cancer. The Epidemiology Laboratory screens germline DNA for genetic polymorphisms, mutations, and other genetic changes that predispose individuals to cancer. Functional assays are also conducted to assess the effects of these genetic changes.


​Molecular Epidemiology Laboratory

Led by Dr. Irene Orlow, the Molecular Epidemiology Laboratory supports investigators from the PSRP and Clinical Research programs, through:
  1. Guidance and recommendations for the procurement and transportation of specimens (sample type, collection tube/vessel, timing and temperature, etc)

  2. Initial processing of specimens (e.g. isolation and aliquoting of blood derived fractions, urine, saliva)

  3. Banking and preparation of specimens for shipment to collaborators and/or outside testing laboratories

  4. Extraction and characterization of DNA/RNA

  5. Experimental testing

New assays can be set up according to the investigational needs and availability of dedicated equipment (e.g. medium throughput genotyping and/or methylation using MassArray, ELISA, comet assay).
Lab Staff