Our research group studies the utility of different methods to characterize the chronic and long-term adverse cardiovascular side effects of conventional and novel cancer therapies. By investigating the use of these tools, we can better understand how cancer therapeutics damage organs such as the heart and skeletal muscles, as well as identify those individuals at high risk of cardiovascular side effects. In doing so, we can design therapeutic interventions to prevent and/or mitigate these devastating side effects.
- Jones LW, Liu Q, Armstrong GT, Ness KK, Yasui Y, Devine K, Tonorezos E, Soares-Miranda L, Sklar CA, Douglas PS, Robison LL, Oeffinger KC. Exercise and risk of major cardiovascular events in adult survivors of childhood Hodgkin lymphoma: a report from the childhood cancer survivor study. Journal of Clinical Oncology. 2014, 32:3643-50.
- Betof AS, Lascola CD, Fowler E, Scarbrough PM, Jones LW*, Dewhirst MW*. Exercise inhibits tumor progression and sensitizes tumors to chemotherapy in orthotoptic models of breast cancer. Journal of the National Cancer Institute. In Press *co-senior authorship.