Komal Rathi

Bioinformatics Engineer II, Leukemia Genomics

Komal Rathi is a Bioinformatics Engineer in Elli Papaemmanuil’s lab. She holds a Masters degree in Bioinformatics from the Johns Hopkins University. Prior to MSK, she has experience working at Penn’s Cardiovascular Institute, where her work involved identifying novel lincRNAs and determining their relationship with known transcription factors in Lung development and Human Heart failure.

Her current work in the leukemia genomics group at MSK includes development and implementation of workflows for RNAseq and variant calling as well as refining existing pipelines for copy number variation detection and analysis of high throughput sequencing data.

She is highly motivated by cancer research as it targets one of the leading causes of death worldwide. Her main goal is to develop bioinformatic pipelines and applications in order to improve genomic analysis, automate data processing and provide better visualization methods for scientists.


Rathi KS, Gaykalova DA, Hennesey P, Califano JA, Ochs MF. “Correcting Transcription Factor Gene Sets for Copy Number and Promoter Methylation Variations”, Drug Development Research. Sep 2014, 75(6): 343-347. doi: 10.1002/ddr.21220

Herriges MJ, Swarr DT, Morley MP, Rathi KS, Peng T, Stewart KM, Morrisey EE. ”Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development”, Genes and Development.  2014 June 15; 28(12):1363-1379. doi:10.1101/gad.238782.114

Snitow ME, Li S, Morley MP, Rathi K, Lu MM, Kadzik RS, Stewart KM, Morrisey EE. “Ezh2 represses the basal cell lineage during lung endoderm development”, Development. 2015 Jan 1;142(1):108-17. doi: 10.1242/dev.116947.

Peng T, Kakzik RS, Morley MP, Rathi KS, Cheng L, Morrisey EE. “Postnatal tissue quiescence is an actively maintained state regulated by hedgehog signaling”, Nature. 2015 Oct 22; 526(7574):578-82. doi: 10.1038/nature.14984.