Pancreatic Cancer Clinical Trials

The purpose of this study is to see whether the combination of melphalan, BCNU, vitamin B12b, and vitamin C, followed by autologous (self) bone marrow stem cell infusion, is safe and effective for treating patients with advanced pancreatic cancer who have a BRCA1 and/or BRCA2 gene mutation. All of these treatments are given intravenously (by vein).

Researchers in this study want to see how a new form of radiation therapy works to treat metastatic cancer. Metastatic means the cancer has spread to another part of the body from its original place. The people in this study have solid tumors that spread to soft tissues in the chest, abdomen (belly), or pelvis. In addition, they need radiation therapy to help control symptoms such as pain.

To learn more about the purpose of this study and to find out who can join, please click here to visit ClinicalTrials.gov for a full clinical trial description.

There are unknown factors in our environment and in people's genes that raise the risk of getting pancreatic cancer. To learn about these things, researchers at Memorial Sloan Kettering Cancer Center created a Pancreatic Tumor Registry. This registry includes people with pancreatic cancer, and also people who have a strong family history of this disease.