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Physician-scientist Alan Hanash studies transplant immunology and immune-mediated mechanisms of tissue damage and regeneration.

… Alan Hanash is an Associate Member of Memorial Sloan Kettering and an Attending Physician on the Adult Bone Marrow Transplant Service in the Department of Medicine. Dr. Hanash’s research focuses on the immunology of hematopoietic transplantation and immune-mediated mechanisms of tissue damage and regeneration

Medical physicist John Humm focuses on noninvasive imaging of the tumor microenvironment using nuclear imaging methods.

… I am head of the nuclear medicine physics section, which supports research in PET/CT, targeted therapies, and molecular imaging. As both a medical and biophysicist, I investigate nuclear imaging methodologies to define tumor targets in terms of their metabolic and microenvironmental properties. I have

Chemical Biologist Minkui Luo develops cutting-edge tools, technologies and concepts to annotate functions of protein-posttranslational modifications and designs inhibitors for cancer therapies.

… The Luo Lab is interested in developing and leveraging novel approaches at the interface of chemistry and biology to annotate functional roles of epigenetic modulators. Epigenetic regulation is essential for maintaining cellular fates and its dysregulation has been associated with various diseases including

Radiologist and Nuclear Medicine physician Jan Grimm develops novel approaches for improved diagnosis, monitoring and therapy of prostate and other cancers.

… The Grimm lab in the Molecular Pharmacology Program focuses on the development of novel and innovative approaches for cancer diagnostics and therapy. These approaches evaluate underlying biology and utilize nanotechnology, chemistry and physics interrogated with modern imaging methods. The lab focuses

Physician-scientist Katharine Hsu studies the biology of human natural killer cells and how they contribute to disease processes.

… My laboratory studies the natural killer (NK) cell and the molecules that control its ability to recognize and kill cancer and virally infected cells. Improved understanding of how NK cells behave is critical to advancing our ability to harness their innate capacity for tumor recognition and eradication

Computational chemist John Chodera uses statistical mechanics, molecular modeling, and automated biophysical experiments to help identify new potential therapeutics and investigate mechanisms of drug resistance in cancer.

… The Chodera lab uses computation and experiments to develop quantitative, multiscale models of the effects of small molecules on biomolecular macromolecules and cellular pathways. To do this, the group utilizes physical models and rigorous statistical mechanics, with the overall goals of engineering

Immunologist Morgan Huse studies the structure and function of immune cell-cell interactions.

… In the Huse lab, we combine imaging technology with synthetic chemistry and materials science to understand how immune cells communicate. Morgan Huse, PhD Deputy Director for Core Technologies; Member, Immunology Program Professor PhD, The Rockefeller University Achievements Searle Scholar Award (2008

Surgeon scientist Vinod Balachandran develops novel immunotherapies for pancreatic cancer.

… Our goal is to discover new ways to stimulate the immune system to treat cancer. We study pancreatic cancer, a model deadly cancer that is refractory to all immunotherapies, as well as nearly all other treatments. We use reverse translation to uncover the biological basis of exceptional response in rare

Physician-scientist Ping Chi studies genetic and epigenetic mechanisms of transcriptional regulation by oncogenic factors in GIST, MPNST, melanoma and other solid tumors.

… It is well recognized that the cellular context contributes to susceptibility to oncogenic transformation mediated by different “driver” oncogenes. The focus of our laboratory is to discover and understand the critical genetic and epigenetic factors that determine the cellular-context-dependent oncogenesis

My research has focused on the development of novel statistical and bioinformatic methodologies that facilitate the study of translational research questions in cancer genomics and immuno-oncology.

… My research has focused on the development of novel statistical and bioinformatic methodologies that facilitate the study of translational research questions in cancer genomics and immuno-oncology. I developed several algorithms including iCluster and FACETS that are widely used in research community