Director of Clinical Investigation, Department of Radiation Oncology
I am a board-certified radiation oncologist who specializes in the treatment of skin cancer (including melanoma) and eye cancer with radiation therapy. I am one of a few radiation oncologists in the country who focus on these diseases. I work closely with a dedicated team of experts. We use advanced radiation techniques to deliver the best possible care to our patients. Some of these techniques include superficial x-ray therapy, electronic and radioisotope-based brachytherapy, stereotactic radiosurgery, and proton therapy. At MSK, we strive to come up with the best solution for even the most rare and challenging problems. I have been a member of the MSK team since 2006. I see patients at Memorial Hospital in Manhattan and MSK Westchester.
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I am an active biomedical researcher. My goal is to develop more effective cancer treatments using radiation therapy. Prior to joining MSK, I was a Howard Hughes Medical Institute Research Scholar in the Radiation Oncology Branch of the National Cancer Institute. There I developed an interest in combining cancer medicines with radiation therapy to make treatment more effective. Along with my colleagues in the Immunology Program and the Departments of Medicine and Surgery at MSK, I have developed several clinical trials. Many of these combine novel targeted and immune therapies with radiation therapy for different cancers.
Another major goal of my research is to find better ways to protect our patients from potential radiation therapy side effects. To do this, I work closely with the Medical Physics Department. Some of these new techniques are more convenient for our patients because fewer treatment sessions are required. We have several clinical trials in this area.
My research has been supported by the American Society for Radiation Oncology, the Lymphoma Research Foundation, and the National Institutes of Health. I have authored chapters in major medical textbooks as well as peer-reviewed research studies in journals. These include the New England Journal of Medicine, the Journal of Clinical Oncology, the Journal of the National Cancer Institute, Clinical Cancer Research, Radiation Research, and the International Journal of Radiation Oncology, Biology, and Physics.
I teach others about radiation oncology and skin cancer. I frequently give invited presentations on these subjects at national and international meetings.
In the Department of Radiation Oncology, I lead the clinical research program as Director of Clinical Investigation. This program enables the study of cutting-edge radiation treatments for cancers of all types, as well as targeted and immune therapies with radiation therapy. They offer a unique opportunity for our patients in their fight against cancer.
- Clinical Expertise: Skin Cancer (melanoma, squamous cell carcinoma, basal cell carcinoma, Merkel cell carcinoma, dermatofibrosarcoma protuberans, cutaneous angiosarcoma, Kaposi sarcoma); Keloid Scar; Eye Cancer (melanoma, squamous cell carcinoma, basal cell carcinoma, Merkel cell carcinoma)
- Awards and Honors: Castle Connolly Top Doctors New York Metro Area (2016-2017); Super Doctors New York Rising Stars
- Languages Spoken: English
- Education: MD, University of Florida
- Residencies: Radiation Oncology - Memorial Sloan Kettering Cancer Center
- Fellowships: National Cancer Institute; Memorial Sloan Kettering Cancer Center
- Board Certifications: Radiation Oncology
Research is integral to our mission at Memorial Sloan Kettering, and clinical trials help us discover better forms of patient care and treatment. For you, this could mean access to a new therapy or therapy combination. Click to see a list of the trials I’m currently leading.
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Clinical Trials Led by Christopher A. Barker
- A Phase II Study of Pembrolizumab Immunotherapy plus Radiation Therapy in Women with Metastatic Triple-Negative Breast Cancer
- A Phase II Study of T-VEC Immunotherapy plus Radiation Therapy in Patients with Melanoma, Merkel Cell Cancer, and Other Solid Tumors with Skin Metastases
- A Phase II Study of Vismodegib plus Radiation Therapy for Locally Advanced Basal Cell Cancers of the Head and Neck
- A Phase III Study of Surgery Followed by Radiation Therapy or Observation in Patients with Neurotropic Melanoma of the Head and Neck
- A Pilot Study of Electronic Skin Surface Brachytherapy for Treating Basal Cell and Squamous Cell Skin Cancers
Clinical Trials Co-Investigated by Christopher A. Barker
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