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Cancer biologist Hans-Guido Wendel pursues both disease-centered and basic discovery research. The disease focus is on lymphocyte malignancies and the basic science arm of the lab explores fundamental mechanisms that control aberrant mRNA translation programs in cancer. Work in these two research areas frequently intersects in surprising ways.
The Goldberg laboratory focuses on structural and biochemical characterization of intracellular vesicle transport.
My research is focused on cellular and molecular mechanisms that control the differentiation, maintenance, and physiological functions of macrophages and monocytes and their roles in tissue homeostasis and disease processes.
The Hadjantonakis laboratory studies pluripotency and cell fate specification, tissue patterning and morphogenesis, in mammalian embryos and stem cell-derived embryo models.
Cancer biologist Andrea Ventura studies non-coding RNAs in cancer and development
We leverage large-scale unbiased profiling including genomics, transcriptomics, proteomics to identify candidate oncogenes and proteins that are pathogenetically relevant in lymphoma.
Physician-scientist Babak Mehrara studies the regulation of lymphatic regeneration after surgery and development of lymphedema.
Physician-scientist Karlo Perica develops cell therapies to treat a wide variety of cancers, focusing on off-the-shelf approaches such as allogeneic CAR T cells and in vivo gene editing.
Jonathan Coleman is a physician-scientist focused on translational research, cancer genomics, and patient-derived organoid models in the study of urologic malignancies. Ongoing work includes the development of local ablative therapies, their influence on the tumor microenvironment, and implications for therapy response.