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The Aviram Lab investigates the molecular mechanisms that protect microorganisms from their own pathogenic invaders.
Yael David’s lab develops and applies methods in chemical biology toward studying epigenetic regulation and its correlation with disease states.
Our team is focused on developing novel tools and approaches for the diagnosis and treatment of cancer using genomics as a guide.
Physician-scientist Liang Deng studies poxvirus interface with the immune system and the development of poxviruses as oncolytic and immunotherapy for cancers.
Computational biologist Dana Pe’er combines single-cell and spatial profiling technologies with machine learning approaches to address fundamental questions in gene regulation, cellular plasticity and cell-cell communication in the contexts of cancer, immunity and development.
Molecular biologist Xiaolan Zhao studies chromosomal organization, genome integrity, DNA replication and repair, dynamic protein modification.
Physician-scientist Emily Cheng studies the molecular mechanisms of cell death and their implications in tumorigenesis, tumor-microenvironment interactions, targeted therapy, and immunotherapy.
We take real-world data, clean it and use it to discover new predictive biomarkers to guide cancer management (often with AI), and then implement these findings in clinical practice.
Surgeon scientist Vinod Balachandran develops novel immunotherapies for pancreatic cancer.
Physician-scientist Ping Chi studies genetic and epigenetic mechanisms of transcriptional regulation by oncogenic factors in GIST, MPNST, melanoma and other solid tumors.