Dr. Mauguen’s methodological research focuses on survival analyses and the prediction of survival endpoints. She is particularly interested in using information from complex covariates such as recurrent events and biomarker evolution. She also worked on improving the diagnostic and prediction of cancer risk by proposing a strategy to define cancer subtypes. Finally, she is working on improving clinical trial design for rare diseases. She is collaborating with clinical investigators from the Department of Pediatrics and the Molecular Imaging and Therapy Service.
R package frailtypack: General Frailty Models: Shared, Joint and Nested Frailty Models with Prediction (first author: Virginie Rondeau)
R package Clonality: Testing for clonal relatedness versus independence of tumors from the same patient (first author: Irina Ostrovnaya)