Dr. Du’s research aims to identify genetic and modifiable predictors of colorectal and endometrial cancers, with the goal of better understanding tumorigenesis and informing improved preventive strategies. She is an active investigator in the Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO), a large collaborative effort including data from over 40,000 participants. Together with researchers from North America, Australia, and Europe, she studies the interplay of genes and environment (e.g., anthropometrics, lifestyle, diet, and medication use) in colorectal cancer. In addition, she leads a pilot project to collect and comprehensively characterize somatic DNA mutations in recurrent and metastatic colorectal tumors, as well as the harmonization of data for circulating biomarkers across GECCO studies. She is also active in the Epidemiology of Endometrial Cancer Consortium (E2C2), a collaborative effort including data from over 45 population-based studies, where she and colleagues are studying diabetes, obesity, and hypertension in the development of endometrial cancer. Beyond cancers, Dr. Du seeks to understand telomere length dynamics—a potential indicator of cellular aging linked to chronic disease—along with their role in cancer. She is carrying out much of these investigations in the Nurses’ Health Study (NHS), a large nationwide cohort of women’s health.