Marinela Capanu, PhD

Associate Attending Biostatistician

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Marinela Capanu, Associate Attending  Biostatistician

Office Phone

646-888-8256

Education

University of Florida

Current Research Interests

Dr. Capanu’s current methodological research interests are in the development of optimized variable selection procedures for regression models. She has recently developed a novel variable selection technique and showed that it has superior performance to competitor methods for low to moderate scale linear regressions. As part of her collaborative work, Dr. Capanu has been involved in clinical collaborations with the Gastrointestinal Oncology Service since joining Memorial Sloan Kettering Cancer Center in 2005. She has assisted the oncologists in this group at every stage in their clinical trials from the design to the statistical analysis and publication of their studies. Dr. Capanu is also assisting investigators in the Department of Radiology with the design and analysis of various projects investigating different imaging modalities and potential biomarkers.

Publications

Selected peer-reviewed publications:

  1. Booth J, Capanu M, Heigenhauser L (2005) Exact conditional p-value calculation for the quasi-symmetry model, Journal of Computational and Graphical Statistics, 14(3):716-725.

  2. Capanu M, Presnell B (2007) Misspecification Tests for Binomial and Beta-Binomial Models, Statistics in Medicine, 27(14):2536-2554

  3. Capanu M, Orlow I, Berwick M, Hummer AJ, Thomas DC, Begg CB (2008) The Use of Hierarchical Models for Estimating Relative Risks of Individual Genetic Variants: An Application to a Study of Melanoma, Statistics in Medicine, 27(11):1973-1992

  4. Capanu M, Begg CB (2011) Hierarchical Modeling for Estimating Relative Risks of Rare Genetic Variants: Properties of the Pseudo-Likelihood Method, Biometrics, 61:371-380

  5. Capanu M, Concannon P, Haile RW, Bernstein L, Malone KE, Lynch CF, Liang X, Teraoka SN, Diep AT, Thomas DC, Bernstein JL; The WECARE Study Collaborative Group, Begg CB (2011) Assessment of rare BRCA1 and BRCA2 variants of unknown significance using hierarchical modeling, Genetic Epidemiology, 35:389-397

Visit PubMed for a full listing of Marinela Capanu’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.