Samantha Brown, MS

Research Biostatistician

Samantha Brown, MS

Research Biostatistician
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Samantha Brown

Education

Columbia University

Current Research Interests

Sammi primarily collaborates with researchers in the Neurosurgery and Bone Marrow Transplant services on retrospective and prospective studies. She is also part of the Statistical Coordinating Center for AACR Project GENIE BPC and is helping to develop the genieBPC R package. Sammi’s research interests include using survival and competing risks analyses to answer questions related to patient outcomes, along with exploring the biases inherent to observational clinico-genomic datasets. Aside from her analytic projects, Sammi is a member of the Bridge to Biostats committee.

Publications

  1. Lavery JA, Brown S, Curry MA, Martin A, Sjoberg DD, Whiting K. A data processing pipeline for the AACR project GENIE biopharma collaborative data with the {genieBPC} R package. Bioinformatics. 2023 Jan 1;39(1):btac796. doi: 10.1093/bioinformatics/btac796. PMID: 36519837; PMCID: PMC9822536.
  2. Elkrief A, Alessi JMV, Ricciuti B, Brown S, Rizvi H, Preeshagul IR, Wang X, Pecci F, Di Federico A, Lamberti G, Egger JV, Chaft JE, Rudin CM, Riely GJ, Kris MG, Ladanyi M, Chen Y, Hellmann MD, Shen R, Awad MM, Schoenfeld AJ. Efficacy of PD-(L)1 blockade monotherapy compared with PD-(L)1 blockade plus chemotherapy in first-line PD-L1-positive advanced lung adenocarcinomas: a cohort study. J Immunother Cancer. 2023 Jul;11(7):e006994. doi: 10.1136/jitc-2023-006994. PMID: 37487667; PMCID: PMC10373730.
  3. Vaughn JL, Brown S, Papadopoulos EB, Jakubowski AA, Tamari R, Giralt SA, Ponce DM, Cho C, Perales MA, Shaffer BC, Gyurkocza B. CD34-selected allogeneic hematopoietic cell transplantation for chronic myeloid leukemia in the tyrosine kinase era. Bone Marrow Transplant. 2022 Nov;57(11):1740-1742. doi: 10.1038/s41409-022-01783-7. Epub 2022 Sep 8. PMID: 36076011.
  4. Brown S, Lavery JA, Shen R, Martin AS, Kehl KL, Sweeney SM, Lepisto EM, Rizvi H, McCarthy CG, Schultz N, Warner JL, Park BH, Bedard PL, Riely GJ, Schrag D, Panageas KS; AACR Project GENIE Consortium. Implications of Selection Bias Due to Delayed Study Entry in Clinical Genomic Studies. JAMA Oncol. 2022 Feb 1;8(2):287-291. doi: 10.1001/jamaoncol.2021.5153. PMID: 34734967; PMCID: PMC9190030.
  5. Wilcox JA, Brown S, Reiner AS, Young RJ, Chen J, Bale TA, Rosenblum MK, Newman WC, Brennan CW, Tabar V, Beal K, Panageas KS, Moss NS. Salvage resection of recurrent previously irradiated brain metastases: tumor control and radiation necrosis dependency on adjuvant re-irradiation. J Neurooncol. 2021 Dec;155(3):277-286. doi: 10.1007/s11060-021-03872-x. Epub 2021 Oct 16. PMID: 34655373.